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Protein Overview: CE290_DANRE

General Information:
Name(s) found: CE290_DANRE [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • Centrosomal protein of 290 kDa OS=Danio rerio GN=cep290 PE=2 SV=1 [Swiss-Prot]
    • Organism: Danio rerio
    Length: 2439 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA][ISS]
    centrosome [ISS]
    cytoskeleton [IEA]
    cytoplasm [IEA]
    Biological Process: pronephros development [IGI][IMP]
    eye development [IMP]
    multicellular organismal development [IEA]
    cerebellum development [IMP]
    hindbrain development [IMP]
    otic vesicle formation [IMP]
    protein transport [IEA]
    eye photoreceptor cell development [IMP]
    transport [IEA]
    gastrulation [IGI]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAAADWRLL MGMDPEDLGD EDEKICDLIL MVKPRDLKAD DSEKMIQLFR ISQTLLRMKL  60
   61 DEIKCAYEVV DSAGAEQARI ENELKAKVLK LESELEMAQR VMGGGDKHFL RDEIRQLESH 120
  121 LERKEKEVTQ LEKEMGKERK SNEELALRAE EAEEKNRKLK REIKQLTRKN EQLQQDIEFY 180
  181 RKEAEQRESL QTKEESNEIQ RRLTKANQQL YQCMEELQHA EDMAANLRSE NEHLQKNLEE 240
  241 SVKEMEKMTD EYNKMKIAVQ QTDAIMDQLR KDRDHAKLQV RELTDQIQAR VEEDDPVMAA 300
  301 VNAKVEEWKS VLSGKDLEIL EYQQMIRDLR EKLRTAQMDS DKSNIIALQQ AVQERDNQIK 360
  361 MLSEQVEQYT TEMERNAMLI EELKRPLKKD KGHSSDHQRR LEDLSAKLQV AERKVLEAQR 420
  421 AAQLAERDAR DKDKELNDTL SRIRLYESGT DGLEAAISEI KECKNQIRVR DREIEGMIKE 480
  481 INQLEMKINN LLDENEDLRE RLGLNPKEEL DLSEFRRSKI LKQRQYKAEN QVLLKEIERL 540
  541 EEERLELKQR IRALVKDKGV TVVSNSLLDN SVEEKPVRSL RPSSGSTDDE IKRKNERLQK 600
  601 ELSNKEKELE LRRSESAQFK AKLNEMLNEN KQLEQGMKEI LQAIQDTQKK TPTSTGVSIP 660
  661 SLERLVNALE MKYSEGKFDA SLHLRTQVDQ LTGRNEELRL EMKTAREEAA NTLSQLTKAN 720
  721 EKIARLESEM ESMSKSTGSS IPHKTLALPE EMTPTSAEAI NALNEYTVQL LQEIKNKGDS 780
  781 IEQLGSALEE YKRKFAVIRH QQGLLYKEHQ SERESWQKER DSFAELKSKL EEQREVDAVK 840
  841 IKEYNHLLET LEKDPSEIRR EMAETGRKIV VLRVNEKCLT RRYTTLLELE QHLRKENAKL 900
  901 KEDFTQMQAV VTERIGYLQR FKEMAAFKMA SLQKSLDVSV PASELERANK QYTELTIKYR 960
  961 NLLQKDNHLV QKTTSLEHLE TENMSLRERI DSINKELEIS KEKLHTLEQA FENISTTGGE1020
 1021 IIMDKATKAV ANSEIVSVSR RITTLEMKEL NERQRAEHAQ KMYEHLRNSL KQVEERNFEL1080
 1081 ETKFAELTKL NLEAQRIERE LRDELADSVS KHISDADRKR ITELEKTEAN LRIEVSKLRE1140
 1141 VSDVAKMQVS ALDARQQSRE KEVESLRRQV LDYQAESDEK ALIAKLHQHI VALQLSETTA1200
 1201 ISRLEATNTR LQKLEAQKLR DEQKLDEQQQ ALWHARQEGH QRARHLRHTI QALRRQFSGA1260
 1261 LPLAQQEKFS NTMLHLQEDR ARVREDAQIA EEERRKAEGK AQELELKLKG LEELIATLKD1320
 1321 AKGAQKVSEW HKKLEDVRLL EMRQSRELNT QREEIKYLKN CVAEQECTIS GLEEELVQQN1380
 1381 NLLEERQLIW DQREVQLERQ LDSYEKQQNE VLNTAQKFEE ATGSLPDPNQ PLANQLDYAL1440
 1441 GKIKEHVRTI LETKTTCKIL EEKLKEKEAA LWSSEQNVLS RDKVINELRL RLPAAAEREK1500
 1501 LLADLSKQED SESQPTLKVA HQTINNLQGR LDQKEEVLKK YQNLLGKARQ EQEEIAKRHE1560
 1561 EEVRALHQKL DVYMDTSLDR FKQTALELIK KPTITVPTSK HLVRLAEMEQ TVAEQDNSLS1620
 1621 SLSQKLKIVT QELDQQRQVT AAQAMEHAAD MARLEDKHAA QMKGLSQEAE ELRAQLIQME1680
 1681 KELHYLRTEL EAQKEANVRS PSNTMKNLVE RLKNQLALKE KQLKALSKAL LELRAELTSQ1740
 1741 AEQQIITNAA QKEEALNVQQ IVDKQTKELR ACVRDLNEEL QLAKDGVRAA KARENSLKED1800
 1801 LETLNKDLQR SQKSQNKLQS EKEALEEHLN ELKKKIQRLS SGLQAQVESD GPTVDSLQKK1860
 1861 IRKLEHELDR KSISEPADKR STLKEDKSSK EEVVRWEEGK KWQARVDKMR NVLKEKEREV1920
 1921 DSQAKQLATM KELYSRLEQE KVSLQKKLKG RGVTADQVVG ARTLEADKEI EELHKRNAEL1980
 1981 EQQIKVMKQQ QALPRDAAME DITIRNRYLE ERLYSMESRL SKEPPSRPST SGRGSDTPSQ2040
 2041 REHEFQKENL RLSTENLELR FQLEQANKDL PRLKDQVSDL KEMCSVLKKE KAEVEKRLSH2100
 2101 LRGSGRSGKT IPELEKTIGL MKKVVEKVQR ENENLKKTSE VNVQEQLATL ERDHEKLKSE2160
 2161 YEKLKGKQEE QLNSRLESKT KGIEKIMMEN ERLRKEIKKE AEAAEKLRVA KASLEVANEK2220
 2221 LKAELEETHQ RLLLAQSKGA TLLGVDSKTW KSSVVTRLFE NKMKGLESDI AKKNISISEL2280
 2281 KVQLKEANEK LQATQHTVIQ LKEQVELLKN VPVEATTDEG LAREYQSVRL ANKQLEREKA2340
 2341 QLLRQIQRNE VQLGTNKDGP GYTELQEQIK AANNEKKKLQ DEVRKLTQEL KHFDPTFFEE2400
 2401 LEDLKFNYNL EVKKNIVLEE QLKKLSDQFG VAIPDVSIN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle