Protein Overview: unc-45

General Information:
Name(s) found:	unc-45 / CE01925 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006781 locus:unc-45 status:Partially_confirmed UniProt:G5EG62 protein_id:CCD69153.1 [WormBase] gi\|861392\|gb\|AAA68407.1\| Uncoordinated protein 45 [Caenorhabditis elegans] [NCBI NR] pir\|\|T32493 unc-45 protein - Caenorhabditis elegans [NCBI NR] gi\|4104228\|gb\|AAD01976.1\| UNC-45 [Caenorhabditis elegans] [NCBI NR] gi\|17555404\|ref\|NP_497205.1\| UNCoordinated family member (unc-45) [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE01925 WBGene00006781 locus:unc-45 P59 protein and TPR domain status:Partially_confirmed TR:Q09981 protein_id:AAA68407.1 [wormpep150.fasta] 01925 WBGene00006781 locus:unc-45 P59 protein and TPR domain status:Partially_confirmed TR:Q09981 protein_id:AAA68407.1 [wormpep130-phg-ecoli-orf-rand.fasta] TPR repeat containing protein associated to myosin B, UNCoordinated locomotion UNC-45 (107.4 kD) (unc-45) [Caenorhabditis elegans]gi\|861392\|gb\|AAA68407.1\| Uncoordinated protein 45 [Caenorhabditis elegans]gi\|4104228\|gb\|AAD01976.1\| UNC-45 [Caenorhabditis [nrdb_11152004_Chlamydomonas] locus:unc-45 P59 protein and TPR domain status:Partially_confirmed TR:Q09981 protein_id:AAA68407.1 [wormpep115.fasta.reversed] CE01925 locus:unc-45 P59 protein and TPR domain status:Partially_confirmed [wormpep80.hongbin] CE01925 WBGene00006781 locus:unc-45 P59 protein and TPR domain status:Partially_confirmed UniProt:Q09981_CAEEL protein_id:AAA68407.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE01925 WBGene00006781 locus:unc-45 P59 protein and TPR domain status:Partially_confirmed UniProt:Q09981_CAEEL protein_id:AAA68407.1\| [wormORF-contam.fasta] UNC-45 [Caenorhabditis elegans] [nr-271106-contam.fasta] Uncoordinated protein 45 [Caenorhabditis elegans] [nr-271106-contam.fasta] UNCoordinated family member (unc-45) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE01925 WBGene00006781 locus:unc-45 P59 protein and TPR domain status:Partially_confirmed UniProt:Q09981 protein_id:AAA68407.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE01925 WBGene00006781 locus:unc-45 P59 protein and TPR domain status:Partially_confirmed UniProt:G5EG62 protein_id:CCD69153.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE01925 WBGene00006781 locus:unc-45 status:Partially_confirmed UniProt:G5EG62 protein_id:CCD69153.1 [wormpep246-ecoli-contam.fasta] UNC-45 OS=Caenorhabditis elegans GN=unc-45 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	961 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] cleavage furrow [IDA] cytoplasm [IEA] cell cortex [IDA] plasma membrane [IDA]
Biological Process:	locomotory behavior [IMP ] locomotion [IGI][IMP ] embryonic development ending in birth or egg hatching [IMP ] positive regulation of growth rate [IMP] protein amino acid dephosphorylation [IEA] sarcomere organization [IGI][IMP] oviposition [IGI][IMP] reproduction [IMP] positive regulation of locomotion [IMP]
Molecular Function:	phosphoprotein phosphatase activity [IEA] ubiquitin protein ligase binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVARVQTAEE IRDEGNAAVK DQDYIKADEL YTEALQLTTD EDKALRPVLY RNRAMARLKR  60
   61 DDFEGAQSDC TKALEFDGAD VKALFRRSLA REQLGNVGPA FQDAKEALRL SPNDKGIVEV 120
  121 LQRLVKANND KIKQTTSLAN KVTDMEKLAF RGEAKDTEQK MTALNNLLVL CRESESGATG 180
  181 VWNQGALVPF VLNLINDASE NEEVTVTAIR ILDETIKNSV RCMKFLAMHD PDGPKSVRFV 240
  241 CRLMCKKSTK DFVDATGILV QRVFNAMAKM DRQKEMKPDP EVAEANKIWI IRVLLELQEM 300
  301 LQDPKVGAVQ RETCIDLFLK NLMHMDGGIP RGWSWKFVEE RGLLALLDVA SQIPELCEYP 360
  361 VSAETRQHVA ICLQRLEEDM VFDTKRTIFK EKVDMFFNAL ISRCTNDDEG HKYRIKLSCF 420
  421 LITMLQGPVD IGINLITNDQ LTPIMLEMAA SQDHLMQGIA AELIVATVSK HERAINMLKV 480
  481 GIPVLRALYD SEDPTVKVRA LVGLCKIGAA GGDDISKATM KEEAVISLAK TCKKFLLETE 540
  541 KYSVDIRRYA CEGLSYLSLD ADVKEWIVDD SLLLKALVLL AKKAGALCVY TLATIYANLS 600
  601 NAFEKPKVDE EMVKLAQFAK HHVPETHPKD TEEYVEKRVR ALVEEGAVPA CVAVSKTESK 660
  661 NALELIARSL LAFAEYEDLR GRIIAEGGTV LCLRLTKEAS GEGKIKAGHA IAKLGAKADP 720
  721 MISFPGQRAY EVVKPLCDLL HPDVEGKANY DSLLTLTNLA SVSDSIRGRI LKEKAIPKIE 780
  781 EFWFMTDHEH LRAAAAELLL NLLFFEKFYE ETVAPGTDRL KLWVLYSAEV EEERLSRASA 840
  841 AGFAILTEDE NACARIMDEI KSWPEVFKDI AMHEDAETQR RGLMGIANIM HSSNKLCSEI 900
  901 VSSEVFRVLV AVTKLGTINQ ERAGSTEQAK RGLEAAEKFG LIKATDREIY ERENQMSTIQ 960
  961 E

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: unc-45

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: