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Protein Overview: mpk-1

General Information:
Name(s) found: mpk-1 / CE01583 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00003401 locus:mpk-1 Mitogen-activated protein kinase mpk-1 status:Confirmed UniProt:P39745 protein_id:CAA87057.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 376 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: vulval development [IGI]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    Ras protein signal transduction [IGI]
    protein amino acid phosphorylation [IEALink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    MAP kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADGEAVIST VNNVEEVHGQ LFEVAPRYVN LSYIGEGAYG MVASALDTIT RDRVAIKKIS  60
   61 PFEHQTFCQR TLREIKILNR FKHENIINIQ EIIRSETVDS LKDIYIVQCL METDLYKLLK 120
  121 TQKLSNDHVC YFLYQILRGL KYIHSANVLH RDLKPSNLLL NTTCDLKICD FGLARVTDPQ 180
  181 TDHTGFLTEY VATRWYRAPE IMLNSKGYTK SIDVWSVGCI LAEMLSNRPL FPGKHYLDQL 240
  241 NLILAVVGSP SNADLQCIIN DKARSYLISL PHKPKQPWAR LYPGADPRAL DLLDKMLTFN 300
  301 PHNRIDIEQA LAHPYLEQYY DPGDEPVCEE PFTLEMEFDD LPKEKLKELI WEEAEAHHRR 360
  361 MEAEAAARNN GGQNPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..376] PSI-BLAST 96.522879 Crystal structure of human ERK2 complexed with a pyrazolopyridazine derivative


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle