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Protein Overview: hda-2

General Information:
Name(s) found: hda-2 / CE01472 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00001835 locus:hda-2 Putative histone deacetylase 2 status:Confirmed UniProt:Q09440 protein_id:CAA86662.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 507 amino acids

    Gene Ontology:
    Cellular Component: histone deacetylase complex [ISSLink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    chromatin modification [ISSLink to PubMed article]
    DNA repair [IMPLink to PubMed article]
    DNA protection [IMPLink to PubMed article]
    histone deacetylation [ISSLink to PubMed article]
    Molecular Function: histone deacetylase activity [ISSLink to PubMed article]
    transcription corepressor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDKFKLDT LFDDNDEIIE PDGADVKKRN VAYYYHKDVG HFHYGQLHPM KPQRLVVCND  60
   61 LVVSYEMPKY MTVVESPKLD AADISVFHTE DYVNFLQTVT PKLGLTMPDD VLRQFNIGED 120
  121 CPIFAGLWDY CTLYAGGSVE GARRLNHKMN DIVINWPGGL HHAKKSEASG FCYVNDIVLG 180
  181 ILELLKYHKR VLYIDIDIHH GDGVQEAFNN SDRVMTVSFH RFGQYFPGSG SIMDKGVGPG 240
  241 KYFAINVPLM AAIRDEPYLK LFESVISGVE ENFNPEAIVL QCGSDSLCED RLGQFALSFN 300
  301 AHARAVKYVK SLGKPLMVLG GGGYTLRNVA RCWALETGVI LGLRMDDEIP GTSLYSHYFT 360
  361 PRLLRPNLVP KMNDANSAAY LASIEKETLA CLRMIRGAPS VQMQNIVGIR LDEIEQIEEN 420
  421 ERLQKSSKSS IEYEVGKVSE KMEEECFVEE DSKPPSFPPG QDPRRIGQYW GYDRSGLAPP 480
  481 RSHSDVIEEA KYEDRDRRKD LNIPGIP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..395] PSI-BLAST 94.221849 No description for 2v5xA was found.
    2 View Details [396..507] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle