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Protein Overview: rnr-2

General Information:
Name(s) found: rnr-2 / CE00874 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00004392 locus:rnr-2 Ribonucleoside-diphosphate reductase small chain status:Confirmed UniProt:P42170 protein_id:CAA84688.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 381 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    deoxyribonucleoside diphosphate metabolic process [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: ribonucleoside-diphosphate reductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLTEIQNVE KENAGASVPK HSSNKLKLEK ELEKLEIVDQ TKAASAEETN NESEVNELDA  60
   61 DEPMLQDLDN RFVIFPLKHH DIWNFYKKAV ASFWTVEEVD LGKDMNDWEK MNGDEQYFIS 120
  121 RILAFFAASD GIVNENLCER FSNEVQVSEA RFFYGFQIAI ENIHSEMYSK LIETYIRDET 180
  181 ERNTLFNAVD EFEFIKKKAD WALRWISDKK ASFAERLIAF AAVEGIFFSG SFASIFWLKK 240
  241 RGLMPGLTHS NELISRDEGL HRDFACLLYS KLQKKLTQQR IYDIIKDAVA IEQEFLTEAL 300
  301 PVDMIGMNCR LMSQYIEFVA DHLLVELGCD KLYKSKNPFD FMENISIDGK TNFFEKRVSE 360
  361 YQRPGVMVNE AERQFDLEAD F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..381] PSI-BLAST 130.0 Ribonucleotide reductase R2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor
    		•  12.7205287868529 bayes_pls_golite062009
  • ribonucleoside-diphosphate reductase activity
    		•  12.6679910771829 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH or CH2 groups
    		•  12.0783326936172 bayes_pls_golite062009
  • class I ribonucleotide reductase activity
    		•  7.27682621818194 bayes_pls_golite062009
  • binding
    		•  2.38747290927526 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.65619019230429 bayes_pls_golite062009
  • DNA binding
    		•  1.60520679245579 bayes_pls_golite062009
  • protein binding
    		•  1.35559475972187 bayes_pls_golite062009
  • ion binding
    		•  0.214820110894452 bayes_pls_golite062009
  • cation binding
    		•  0.203880627974907 bayes_pls_golite062009
  • metal ion binding
    		•  0.203880627974907 bayes_pls_golite062009
  • catalytic activity
    		•  0.197328811494233 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.168785605665701 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.24

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle