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Protein Overview: ger-1

General Information:
Name(s) found: ger-1 / CE00804 [WormBase]
Description(s) found:
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  • WBGene00019813 locus:ger-1 status:Confirmed UniProt:G5EER4 protein_id:CCD69286.1 [WormBase]
  • pir||T16645 hypothetical protein R01H2.5 - Caenorhabditis elegans [NCBI NR]
  • gi|458994|gb|AAA50647.1| Gdp-keto-6-deoxymannose 3,5-epimerase/4-reductase protein 1 [Caenorhabditis elegans] [NCBI NR]
  • gi|17554428|ref|NP_498540.1| GDP-keto-6-deoxymannose 3,5-Epimerase/4-Reductase family member (ger-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|103421859|emb|CAJ77755.1| GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE00804 WBGene00019813 status:Partially_confirmed TR:Q21632 protein_id:AAA50647.1 [wormpep150.fasta]
  • 00804 WBGene00019813 status:Partially_confirmed TR:Q21632 protein_id:AAA50647.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • tissue specific transplantation antigen p35B like (3I150) [Caenorhabditis elegans]gi|458994|gb|AAA50647.1| Hypothetical protein R01H2.5 [Caenorhabditis elegans]gi|7445368|pir||T16645 hypothetical protein R01H2.5 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • status:Partially_confirmed TR:Q21632 protein_id:AAA50647.1 [wormpep115.fasta.reversed]
  • CE00804 status:Predicted TR:Q21632 protein_id:AAA50647.1 [wormpep80.hongbin]
  • CE00804 WBGene00019813 locus:ger-1 status:Confirmed UniProt:Q21632_CAEEL protein_id:AAA50647.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE00804 WBGene00019813 locus:ger-1 status:Confirmed UniProt:Q21632_CAEEL protein_id:AAA50647.1| [wormORF-contam.fasta]
  • CE00804 WBGene00019813 locus:ger-1 status:Partially_confirmed TR:Q21632 protein_id:AAA50647.1 [wormpep160-contam.fasta]
  • GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4- reductase [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • GDP-keto-6-deoxymannose 3,5-Epimerase/4-Reductase family member (ger-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein R01H2.5 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE00804 WBGene00019813 locus:ger-1 status:Confirmed TR:Q21632 protein_id:AAA50647.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE00804 WBGene00019813 locus:ger-1 status:Confirmed UniProt:Q21632 protein_id:AAA50647.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase OS=Caenorhabditis elegans GN=ger-1 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • CE00804 WBGene00019813 locus:ger-1 status:Confirmed UniProt:G5EER4 protein_id:CCD69286.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase OS=Caenorhabditis elegans GN=ger-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 315 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: carbohydrate metabolic process [IEALink to PubMed article]
    GDP-L-fucose biosynthetic process [IDALink to PubMed article]
    nucleotide-sugar metabolic process [IEALink to PubMed article]
    galactose metabolic process [IEALink to PubMed article]
    steroid biosynthetic process [IEALink to PubMed article]
    cellular metabolic process [IEALink to PubMed article]
    Molecular Function: NADP or NADPH binding [IEALink to PubMed article]
    3-beta-hydroxy-delta5-steroid dehydrogenase activity [IEALink to PubMed article]
    coenzyme binding [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    UDP-glucose 4-epimerase activity [IEALink to PubMed article]
    steroid delta-isomerase activity [IEALink to PubMed article]
    dTDP-glucose 4,6-dehydratase activity [IEALink to PubMed article]
    ADP-glyceromanno-heptose 6-epimerase activity [IEALink to PubMed article]
    GDP-L-fucose synthase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTILVTGGT GLVGSAIKKV VETTEKRDDE KWVFIGSKDC DLENLEETRE LFESVKPTHV  60
   61 IHLAAMVGGL FHNLAHNLQF FRKNMAINDN VLALCHEFDV IKCVSCLSTC IFPDKTSYPI 120
  121 DETMVHLGPP HDSNFGYSYA KRMIDVLNKG YAQEHGRKYT SVVPCNVFGP HDNYNLQSGH 180
  181 VLPALIHKAY VAQRDGTPLQ VYGSGTPLRQ FIYSIDLARL FIRVVREYED VEPIILSVNE 240
  241 SDEVSIRDAV SAVVKAIDFT GDVEYDTSKA DGQFKKTASN EKLLKLFPDF QFTPFEQAIQ 300
  301 ESVQWFVDNY ETARK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..315] PSI-BLAST 59.0 GDP-4-keto-6-deoxy-d-mannose epimerase/reductase (GDP-fucose synthetase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • protein binding
    		•  0.381642189238843 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.49

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle