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Protein Overview: CE00548

General Information:
Name(s) found: CE00548 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00018846 locus:eef-1B.1 Probable elongation factor 1-beta\/1-delta 1 status:Confirmed UniProt:P34460 protein_id:CCD63459.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 213 amino acids

    Gene Ontology:
    Cellular Component: eukaryotic translation elongation factor 1 complex [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    translational elongation [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: translation elongation factor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVADVKSPAG LAAFNTTLAE QAFATGFVLS GEDAQLFAAL GSAPNASTYP NVARWYANVA  60
   61 SYTDAERKTW ASAGGSAPAA AAADGDDFDL FGSDDEEEDA EKAKIVEERL AAYAEKKAKK 120
  121 AGPIAKSSVI LDVKPWDDET DLGEMEKLVR SIEMDGLVWG GAKLIPIGYG IKKLQIITVI 180
  181 EDLKVSVDDL IEKITGDFED HVQSVDIVAF NKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] PSI-BLAST 10.522879 Class delta GST
    2 View Details [80..213] PSI-BLAST 39.045757 SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.25677962636026 bayes_pls_golite062009
  • transferase activity
    		•  1.05573069897577 bayes_pls_golite062009
  • catalytic activity
    		•  0.963623964325467 bayes_pls_golite062009
  • protein binding
    		•  0.509172505892898 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.46030380837916 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  0.44372379417457 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.385619646192102 bayes_pls_golite062009
  • glutathione transferase activity
    		•  0.20688408808374 bayes_pls_golite062009
  • DNA binding
    		•  0.175092771820973 bayes_pls_golite062009
    2
    Term Confidence Notes
  • translation elongation factor activity
    		•  12.3173391557088 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  7.81664120156021 bayes_pls_golite062009
  • translation regulator activity
    		•  7.77673515271111 bayes_pls_golite062009
  • actin binding
    		•  3.32293986705361 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.89895269798148 bayes_pls_golite062009
  • binding
    		•  2.63855036019658 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.61354904861592 bayes_pls_golite062009
  • protein binding
    		•  0.590516949627746 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle