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Protein Overview: cts-1

General Information:
Name(s) found: cts-1 / CE00513 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00000833 locus:cts-1 Probable citrate synthase, mitochondrial status:Confirmed UniProt:P34575 protein_id:CAA83004.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    tricarboxylic acid cycle [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: citrate (Si)-synthase activity [IEALink to PubMed article]
    transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSGMAIRR LITKGVIPVC QVAPLSTSAE GSTNLKEVLS KKIPAHNAKV KSFRTEHGST  60
   61 VVQNVNIDMI YGGMRSMKGM VTETSVLDPE EGIRFRGYSI PECQKLLPKA KGGEEPLPEA 120
  121 IWWLLCTGDV PSEAQTAAIT KEWNARADLP THVVRMLDNF PDNLHPMAQF IAAIAALNNE 180
  181 SKFAGAYARG VAKASYWEYA YEDSMDLLAK LPTVAAIIYR NLYRDGSAVS VIDPKKDWSA 240
  241 NFSSMLGYDD PLFAELMRLY LVIHSDHEGG NVSAHTSHLV GSALSDPYLS FSAAMAGLAG 300
  301 PLHGLANQEV LVFLNKIVGE IGFNYTEEQL KEWVWKHLKS GQVVPGYGHA VLRKTDPRYE 360
  361 CQREFALKHL PNDDLFKLVS TLYKITPGIL LEQGKAKNPW PNVDSHSGVL LQYFGMTEMS 420
  421 FYTVLFGVSR ALGCLSQLIW ARGMGLPLER PKSHSTDGLI KLALAAKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..468] PSI-BLAST 142.0 CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF TWO DIFFERENT FORMS OF CITRATE SYNTHASE AT 2.7 AND 1.7 ANGSTROMS RESOLUTION

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • citrate (Si)-synthase activity
    		•  7.90380661459876 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  7.35970609422108 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  4.98392594633005 bayes_pls_golite062009
  • catalytic activity
    		•  2.51855037019879 bayes_pls_golite062009
  • transferase activity
    		•  2.22659761972612 bayes_pls_golite062009
  • binding
    		•  1.15467737113069 bayes_pls_golite062009
  • protein binding
    		•  0.210158634792359 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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