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Protein Overview: rnr-1

General Information:
Name(s) found: rnr-1 / CE00331 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00004391 locus:rnr-1 Ribonucleoside-diphosphate reductase large subunit status:Confirmed UniProt:Q03604 protein_id:CAA79574.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 788 amino acids

    Gene Ontology:
    Cellular Component: ribonucleoside-diphosphate reductase complex [IEALink to PubMed article]
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed article]
    DNA replication [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ribonucleoside-diphosphate reductase activity [IEALink to PubMed article]
    cobalamin binding [IEALink to PubMed article]
    class II ribonucleotide reductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRYNSTYVV KRDGRKEDVH FDKITSRIQK LSYGLNMDFV DPVAVAIKVI SGLYKGVTTV  60
   61 ELDNLAAETA ASMTTQHPEY ALLAARIAVS NLHKKTNKVF SEVMKTLHEF HHPHTGKHAP 120
  121 MISDETWAII EKNADKLNSA IVYDRDYSYT YFGFKTLERS YLLKINKEIV ERPQQMLMRV 180
  181 SIGIHGDDIT SAIETYNLMS ERYMTHASPT LFNSGTCRPQ MSSCFLLTMS EDSILGIYDT 240
  241 LKQCALISKS AGGIGLNVHK IRATGSVIAG TNGTSNGLIP MLRVYNNTAR YVDQGGNKRP 300
  301 GAFAIYLEPW HADIFEFVSL RKNTGPEEER ARDLFLALWI PDLFMKRVEK DQEWSLMCPC 360
  361 ECPGLDDCWG EEFEALYAKY EAEGRVRKTV KARKLWEHIV SNQIETGLPY ITYKDAANRK 420
  421 SNQQNLGTIK CSNLCTEIIE YSAPDEIAVC NLASIALNRY VTPEKKFDFV KLAEVTKVIT 480
  481 RNLNKIIDVN YYPVEEARNS NMRHRPIGLG VQGLADCFML MRYPFTSAEA RDLNKRIFET 540
  541 IYYAALEASC ELAELNGPYS TYEGSPVSKG QLQFDMWGVT PTDQCDWATL RKKIAKHGIR 600
  601 NSLLMAPMPT ASTAQILGNN ESIEPYTSNI YSRRVLSGDF QIVNPHMLKD LVERGLWTDE 660
  661 MKNRLIANNG SIQNIDGIPS DIKELYRTVW EISQKDIIEM AADRGAYIDQ SQSLNIHMAK 720
  721 PSYAGITSMH FYGWKKGLKT GMYYLRTKPA VNAVQFTVDK NALKTNQQAE TPATVAESQD 780
  781 EGCLMCSG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..788] PSI-BLAST 1000.0 Structures of Yeast Ribonucloetide Reductase I


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle