Protein Overview: nbs1

General Information:
Name(s) found:	nbs1 / SPBC6B1.09c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	gi\|68012224\|ref\|NP_001018823.1\| Mre11 complex subunit Nbs1 [Schizosaccharomyces pombe] [NCBI NR] gi\|38258894\|sp\|O43070.3\|NBS1_SCHPO RecName: Full=DNA repair and telomere maintenance protein nbs1 [NCBI NR] gi\|33342052\|dbj\|BAC80248.1\| Nbs1 [Schizosaccharomyces pombe] [NCBI NR] gi\|30525825\|gb\|AAP32157.1\| Nbs1p [Schizosaccharomyces pombe] [NCBI NR] gi\|29603355\|emb\|CAD88196.1\| Mre11 complex subunit Nbs1 [Schizosaccharomyces pombe] [NCBI NR] Mre11 complex subunit Nbs1 [Sanger Pombe] DNA repair and telomere maintenance protein nbs1 OS=Schizosaccharomyces pombe GN=nbs1 PE=1 SV=3 [Swiss-Prot] Nbs1p (Nbs1) (SPBC6B1.09c protein) [pompep4896] Nbs1 protein (SPBC6B1.09c protein) [hmr_yeast5_DM3-1_pombe.fasta] DNA repair and telomere maintenance protein nbs1 [4896.FASTAC] \|nbs1\|\|FHA domain (phosphopeptide binding)\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] FHA domain (phosphopeptide binding); low complexity region (C-terminal); similar to human NBS1 (PMID 12944482); similar to S. cerevisiae YDR369C; involved in DNA repair (PMID 12944482); involved in cell cycle checkpoint (predicted); involved in intra-S ph [nrdb_11152004_Chlamydomonas] \|nbs1\|\|FHA domain \|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pompep2242005.fasta] (Q86ZQ0) Nbs1p (Nbs1) (SPBC6B1.09c protein) [pompep4896_normal_reversed] \|nbs1\|slr10\|Mre11 complex subunit Nbs1\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] Nbs1p [Schizosaccharomyces pombe] [nr-271106-contam.fasta] hypothetical protein SPBC6B1.09c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] Nbs1 [Schizosaccharomyces pombe] [nr-271106-contam.fasta] SPBC6B1.09c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] DNA repair and telomere maintenance protein nbs1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nbs1 PE=1 SV=3 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	613 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] chromosome, telomeric region [IEA] Mre11 complex [IDA]
Biological Process:	DNA damage checkpoint [IDA] double-strand break repair via homologous recombination [IGI] telomere maintenance [IDA] intra-S DNA damage checkpoint [IMP] meiotic DNA double-strand break formation [TAS] regulation of histone phosphorylation [IGI]
Molecular Function:	protein binding [IPI ]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWIIEAEGDI LKGKSRILFP GTYIVGRNVS DDSSHIQVIS KSISKRHARF TILTPSEKDY  60
   61 FTGGPCEFEV KDLDTKFGTK VNEKVVGQNG DSYKEKDLKI QLGKCPFTIN AYWRSMCIQF 120
  121 DNPEMLSQWA SNLNLLGIPT GLRDSDATTH FVMNRQAGSS ITVGTMYAFL KKTVIIDDSY 180
  181 LQYLSTVKES VIEDASLMPD ALECFKNIIK NNDQFPSSPE DCINSLEGFS CAMLNTSSES 240
  241 HHLLELLGLR ISTFMSLGDI DKELISKTDF VVLNNAVYDS EKISFPEGIF CLTIEQLWKI 300
  301 IIERNSRELI SKEIERLKYA TASNSTPQKI IQPQRHIQKN IVDDLFSVKK PLPCSPKSKR 360
  361 VKTLENLSIM DFVQPKQMFG KEPEGYLSNQ SNNGSAQNKK SGDNSEKTKN SLKSSSKKSA 420
  421 NTGSGQGKTK VEYVSYNSVD KGNSSPFKPL ELNVVGEKKA NAEVDSLPSE NVQESEDDKA 480
  481 FEENRRLRNL GSVEYIRIMS SEKSNANSRH TSKYYSGRKN FKKFQKKASQ KAPLQAFLSL 540
  541 SEHKKTEVFD QDDTDLEPVP RLMSKVESIP AGASSDKSGK SSISKKSSNS FKELSPKTNN 600
  601 DEDDEFNDLK FHF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: nbs1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: