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Protein Overview: xlf1

General Information:
Name(s) found: xlf1 / SPCC24B10.14c [Sanger Pombe]
Description(s) found:
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  • gi|7160259|emb|CAB76223.1| xrcc4 like factor, cernunnon [Schizosaccharomyces pombe] [NCBI NR]
  • gi|50401795|sp|Q9P7J2.1|XLF1_SCHPO Xrcc4-like factor 1 (Non-homologous end-joining protein 1) (Meiotically up-regulated gene 104 protein) [NCBI NR]
  • gi|19075517|ref|NP_588017.1| xrcc4 like factor [Schizosaccharomyces pombe] [NCBI NR]
  • gi|11289217|pir||T50421 hypothetical protein SPCC24B10.14c [imported] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • xrcc4 like factor [Sanger Pombe]
  • Hypothetical protein C24B10.14c in chromosome III - Schizosaccharomyces pombe (Fission yeast) [Swiss-Prot]
  • Xrcc4-like factor 1 OS=Schizosaccharomyces pombe GN=xlf1 PE=1 SV=1 [Swiss-Prot]
  • HYPOTHETICAL PROTEIN; SEQUENCE ORPHAN: Q9P7J2; [pompepVF.fasta]
  • Hypothetical protein [pompep4896]
  • |||hypothetical protein [pompepnew.fasta]
  • Hypothetical protein C24B10.14c in chromosome III [4896.FASTAC]
  • |||sequence orphan|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|7160259|emb|CAB76223.1| SPCC24B10.14c [Schizosaccharomyces pombe]gi|11289217|pir||T50421 hypothetical protein SPCC24B10.14c [imported] - fission yeast (Schizosaccharomyces pombe)gi|50401795|sp|Q9P7J2|Y [nrdb_11152004_Chlamydomonas]
  • (Q9P7J2) Hypothetical protein [pompep4896_normal_reversed]
  • |xlf1|nej1, mug104|xrcc4 like factor, cernunnon|Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPCC24B10.14c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPCC24B10.14c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |xlf1|nej1, mug104|xrcc4 like factor|Schizosaccharomyces pombe|chr 3|||Manual [spombe-190209-contam.fasta]
  • Xrcc4-like factor 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=xlf1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 203 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    DNA ligase IV complex [TASLink to PubMed article]
    Biological Process: [NOT]double-strand break repair via homologous recombination [IMPLink to PubMed article]
    double-strand break repair via nonhomologous end joining [IGILink to PubMed article]
    double-strand break repair [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWVQLRGHR FHFIQASFDA ESNEAVQVIH ITDLVRVWSC TCSRNQIVNQ AESERCPIDP  60
   61 FQTFETLVDV LAEVLVNVSS ESRIQLRGSN DEGSLKIFCT SKIAKDIFLE WNWTLWLTPP 120
  121 ETIAKMVWFP LINHHLFESE TDTSPGSLMS IIRDQKSLLN DKTWFKEALN ERSSSSNPST 180
  181 PRKRSAFADI ISPKRPRTRY DFV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] FFAS03 1.24 XRCC4, N-terminal domain; XRCC4, C-terminal oligomerization domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.62853926989034 bayes_pls_golite062009
  • DNA binding
    		•  1.60352768462984 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.59639378096494 bayes_pls_golite062009
  • protein C-terminus binding
    		•  0.795373170462144 bayes_pls_golite062009
  • protein binding
    		•  0.603915344378852 bayes_pls_golite062009
  • catalytic activity
    		•  0.532570324528821 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle