Protein Overview: nnt1

General Information:
Name(s) found:	nnt1 / SPAC8F11.09c [Sanger Pombe]
Description(s) found: Found 19 descriptions. SHOW ALL	nicotinamide N-methyltransferase Nnt1 [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	255 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [ISS] cytosol [IDA]
Biological Process:	nicotinamide metabolic process [ISS] chromatin silencing at rDNA [ISS]
Molecular Function:	nicotinamide N-methyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADNDFEGFG IFEEPEGFRP STPPPKEVLH TRVIVPNGPE EIKLRLVGSH SLWAHYLWNS  60
   61 GIELANYIDK NPDTVRAKKV LELGAGAGLP SIVSAFDGAK FVVSTDYPDP ALIDNLEHNV 120
  121 KQYAEIASKI SAVGYLWGSN IKEVMSNAGF KDNEVFDILL LSDLVFNHTE HSKLIKSCKM 180
  181 AIEGNPNAVV YVFFTHHRPH LAKKDMIFFD IAQSEGFQIE KILEEKRTPM FEEDPGAPEI 240
  241 RATVHGYKMT IPIPV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..255]	PSI-BLAST	25.0	Crystal Structure of RumA, the iron-sulfur cluster containing E. coli 23S Ribosomal RNA 5-Methyluridine Methyltransferase

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
transferase activity	1.77671966857605	bayes_pls_golite062009
DNA-methyltransferase activity	1.4114792557994	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	1.07629237539972	bayes_pls_golite062009
methyltransferase activity	1.06467956103007	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.04881630872808	bayes_pls_golite062009
transcription regulator activity	0.978540537169703	bayes_pls_golite062009
DNA binding	0.905031018963259	bayes_pls_golite062009
nucleic acid binding	0.848300230574943	bayes_pls_golite062009
histone methyltransferase activity	0.718593815666209	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.488694756043017	bayes_pls_golite062009
RNA methyltransferase activity	0.473668177706488	bayes_pls_golite062009
N-methyltransferase activity	0.344664739778274	bayes_pls_golite062009
binding	0.336188540273603	bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity	0.155715313885332	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.0598613771472298	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle