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Protein Overview: msh6

General Information:
Name(s) found: msh6 / SPCC285.16c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • MutS protein homolog [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1254 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: maintenance of DNA repeat elements [IMPLink to PubMed article]
    mismatch repair [IMPLink to PubMed article]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    guanine/thymine mispair binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVGNVGKQR EKTKDSSAKT KQKTLFGFFS KIPNVKQEKS DSTLSSSSNH DSNHDTPADV  60
   61 DNSSNVNKNS SSPERELPTS PSHHANTEID SSSSMLPPPS SDPFSSPLSS SLHRSSPKRP 120
  121 HDSLGEESPG KLLRTSVKQE PDSEEEIDSP TKKKSFKSLD TSIFQAEDQF RHPVSSKLEN 180
  181 SELSEVDKPF IASRRSRKPV SYAESDEDED FDDAPTKGSR HKRIVSDDES DDYVEPDHIS 240
  241 EASSEASLPI DEVESMDEDV DGYSDHSVSV AAPIPKKESR KESSNSLYES YRLGSQIASP 300
  301 SPSVSGSASP TKSNKNGVLN REEKRRQRME AFKKENNERY EWLLDVRDAD QNRVGDPNYD 360
  361 PRTLYIPPSA WATFKPFEKQ FWKIKKDLMD TVVFFQKGKF YELYENDAAI GHQVFSLKLT 420
  421 DRVNMKMVGI PEASFDYWAS QFIAKGYRIA RVDQLETALG KEIKDRQRTQ KEEKVVQRGL 480
  481 TQVLTSGTLV DEAMLTSDLS TYCMAIKESL QSDNEEPSFG ICFIDTSTGG FHMCEFTDDI 540
  541 HRTKLDTLLT QVRPKELILE KSKISQKSIR AIKYCVSSSS IWNFIKPYTE FWDNERVERE 600
  601 IIAGDYFKNG LEGAPKILKS YLSEKPLAIS AFGALFWYLR QLKLDKDMCS MGNFDEYDAS 660
  661 QQSTSLLMNG QTLKNLEIFS NSFDGGSEGT LFHLLCRCVT PFGKRLFHTW LCHPLRSGTA 720
  721 INARLDVVEL IADNPVIRDT IWGFLHKLPD LERLISRVHA GRSKPADFVR VLEGFQRINS 780
  781 AFDQLREEFM EVAEGTLLGE IIQSAPNMKE ELEAWTRAFN WQKASEEGVF EPEIGFEAEY 840
  841 DTSQKYQSEL KNELYALLEQ YKKQLRCSSL NFKNIGKEVY QVEVPSDVKV PVNWCKMSGT 900
  901 KKTNRYYNDE LRKKIKKLLE AEELHLAIMS RMQEKFYIRF DSNYEQWLAL IKYTASIDCF 960
  961 FSLSQAAAAL GEPYCRPEII EQKDGHLYFE ELRHPCINAS AASTFVPNDV VLGGESPNMI1020
 1021 VLTGPNMAGK STLLRQVCIA VIMAQLGCWV PAKRASITPM TSIYTRLGAN DDIMSARSTF1080
 1081 MVELSETKKI LDECGPKSLV ILDELGRGTS TYDGHAIAYA VLHHLVSNIG CLGFFSTHYQ1140
 1141 SLCVDFMHHR QVRLMQMAAA VDEKIRRVTF LYKLEDGICP KSYGMNVASM AGLPEKVIDA1200
 1201 AEEKASELEQ ASASFINASD DIALMSDFLQ VLRISKSIEP LTAVNIPLIL DSFE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] MSA 9.353996 View MSA. No confident structure predictions are available.
    2 View Details [203..282] deduced N/A No confident structure predictions are available.
    3 View Details [283..1254] PSI-BLAST 1000.0 No description for 2o8bB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle