YRC Public Data Repository - Protein Structure Prediction

Protein:	msh6
Organism:	Schizosaccharomyces pombe
Length:	1254 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for msh6.

Description	E-value	Query Range	Subject Range
MUTS_ERWCT - DNA mismatch repair protein mutS OS=Erwinia carotovora subsp. atroseptica GN=mutS PE=3 SV=1 MUTS_PECAS - DNA mismatch repair protein MutS OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN...	919.0	[0..370]	[1253..8]
MUTS_CLOTH - DNA mismatch repair protein MutS OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 10...	917.0	[0..371]	[1253..1]
gi\|205324663, gi... - gi\|205324663\|gb\|EDZ12502.1\| DNA mismatch repair protein MutS [Salmonella enterica subsp. enterica se... gi\|167993148, gi... - gi\|205328749\|gb\|EDZ15513.1\| DNA mismatch repair protein MutS [Salmonella enterica subsp. enterica se... gi\|168242649, gi... - gi\|205338197\|gb\|EDZ24961.1\| DNA mismatch repair protein MutS [Salmonella enterica subsp. enterica se... MUTS_SALCH - DNA mismatch repair protein MutS OS=Salmonella choleraesuis (strain SC-B67) GN=mutS PE=3 SV=1 lcl\|NC_016856.1_... - [gene=mutS] [protein=DNA mismatch repair protein] [protein_id=YP_005239020.1] [location=3070516..307... MUTS_SALTY - DNA mismatch repair protein mutS OS=Salmonella typhimurium GN=mutS PE=1 SV=1 MUTS_SALCH - DNA mismatch repair protein mutS OS=Salmonella choleraesuis GN=mutS PE=3 SV=1 MUTS_SALCH - DNA mismatch repair protein mutS OS=Salmonella choleraesuis GN=mutS PE=3 SV=1 MUTS_SALTI - DNA mismatch repair protein MutS OS=Salmonella typhi GN=mutS PE=3 SV=1 MUTS_SALG2 - DNA mismatch repair protein MutS OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=mutS PE=3 ... MUTS_SALTY - DNA mismatch repair protein MutS OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=... gi\|213854165 - gi\|213854165\|ref\|ZP_03382697.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser... MUTS_SALTY - DNA mismatch repair protein mutS OS=Salmonella typhimurium GN=mutS PE=1 SV=1 MUTS_SALPB - DNA mismatch repair protein mutS OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=mutS PE=... MUTS_SALPB - DNA mismatch repair protein MutS OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=mutS PE=... MUTS_SALTI - DNA mismatch repair protein mutS OS=Salmonella typhi GN=mutS PE=3 SV=1 gi\|168463951, gi... - gi\|195633763\|gb\|EDX52177.1\| DNA mismatch repair protein MutS [Salmonella enterica subsp. enterica se... MUTS_SALHS - DNA mismatch repair protein MutS OS=Salmonella heidelberg (strain SL476) GN=mutS PE=3 SV=1 gi\|29143167, gi\|... - gi\|29143167\|ref\|NP_806509.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica serova... MUTS_SALA4 - DNA mismatch repair protein MutS OS=Salmonella agona (strain SL483) GN=mutS PE=3 SV=1 gi\|16761683 - gi\|16761683\|ref\|NP_457300.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica serova... gi\|197240275, gi... - gi\|197262020\|ref\|ZP_03162094.1\| DNA mismatch repair protein MutS [Salmonella enterica subsp. enteric...	912.0	[0..369]	[1254..7]
MUTS_SALPA - DNA mismatch repair protein mutS OS=Salmonella paratyphi A GN=mutS PE=3 SV=1 MUTS_SALPA - DNA mismatch repair protein MutS OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=mutS PE=3 ...	912.0	[0..369]	[1254..7]
MUTS_PHOLL - DNA mismatch repair protein mutS OS=Photorhabdus luminescens subsp. laumondii GN=mutS PE=3 SV=1 MUTS_PHOLL - DNA mismatch repair protein MutS OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CI...	912.0	[0..366]	[1254..2]
gi\|7512474, gi\|2... - pir\|\|JC5839 GTBP-N protein - human, gi\|2696086\|dbj\|BAA23674.1\| GTBP-N [Homo sapiens]	907.0	[0..19]	[1241..1]
gi\|77976003, gi\|... - gi\|77976003\|ref\|ZP_00831536.1\| COG0249: Mismatch repair ATPase (MutS family) [Yersinia frederiksenii...	906.0	[0..366]	[1254..2]
gi\|22124746, gi\|... - gi\|22124746\|ref\|NP_668169.1\| DNA mismatch repair protein [Yersinia pestis KIM], gi\|21957565\|gb\|AAM84... gi\|218930372, gi... - gi\|218930372\|ref\|YP_002348247.1\| DNA mismatch repair protein MutS [Yersinia pestis CO92], gi\|1612350... gi\|45435046, gi\|... - gi\|45440190\|ref\|NP_991729.1\| DNA mismatch repair protein [Yersinia pestis biovar Microtus str. 91001... MUTS_YERPG - DNA mismatch repair protein MutS OS=Yersinia pestis bv. Antiqua (strain Angola) GN=mutS PE=3 SV=1 gi\|167469363 - gi\|167469363\|ref\|ZP_02334067.1\| DNA mismatch repair protein MutS [Yersinia pestis FV-1] gi\|167423797, gi... - gi\|167423797\|ref\|ZP_02315550.1\| DNA mismatch repair protein MutS [Yersinia pestis biovar Mediaevalis... gi\|149289239, gi... - gi\|153997602\|ref\|ZP_02022702.1\| DNA mismatch repair protein MutS [Yersinia pestis CA88-4125], gi\|149... MUTS_YERPP - DNA mismatch repair protein MutS OS=Yersinia pestis (strain Pestoides F) GN=mutS PE=3 SV=1 gi\|166010151, gi... - gi\|166010151\|ref\|ZP_02231049.1\| DNA mismatch repair protein MutS [Yersinia pestis biovar Antiqua str... MUTS_YERPE - DNA mismatch repair protein MutS OS=Yersinia pestis GN=mutS PE=3 SV=1 gi\|165922488, gi... - gi\|165925876\|ref\|ZP_02221708.1\| DNA mismatch repair protein MutS [Yersinia pestis biovar Orientalis ... gi\|229695346, gi... - gi\|229838980\|ref\|ZP_04459139.1\| methyl-directed mismatch repair protein [Yersinia pestis biovar Orie... gi\|167421538, gi... - gi\|167421538\|ref\|ZP_02313291.1\| DNA mismatch repair protein MutS [Yersinia pestis biovar Orientalis ... gi\|229687039, gi... - gi\|229899547\|ref\|ZP_04514688.1\| methyl-directed mismatch repair protein [Yersinia pestis biovar Orie... gi\|166205736, gi... - gi\|166212949\|ref\|ZP_02238984.1\| DNA mismatch repair protein MutS [Yersinia pestis biovar Antiqua str... gi\|165936708, gi... - gi\|89105881\|ref\|ZP_01178393.1\| COG0249: Mismatch repair ATPase (MutS family) [Yersinia pestis biovar... MUTS_YERPN - DNA mismatch repair protein MutS OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=mutS PE=3 SV=1	905.0	[0..366]	[1254..2]
MUTS_YERPS - DNA mismatch repair protein MutS OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=mutS ... MUTS_YERP3 - DNA mismatch repair protein MutS OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=m... MUTS_YERPS - DNA mismatch repair protein mutS OS=Yersinia pseudotuberculosis GN=mutS PE=3 SV=1 MUTS_YERPB - DNA mismatch repair protein MutS OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=mutS P...	905.0	[0..366]	[1254..2]
MSH6_MOUSE - DNA mismatch repair protein Msh6 OS=Mus musculus GN=Msh6 PE=1 SV=3	904.0	[0..19]	[1220..1]

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Predicted Domain #1

Region A:
Residues: [1-202]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVGNVGKQR EKTKDSSAKT KQKTLFGFFS KIPNVKQEKS DSTLSSSSNH DSNHDTPADV  60
   61 DNSSNVNKNS SSPERELPTS PSHHANTEID SSSSMLPPPS SDPFSSPLSS SLHRSSPKRP 120
  121 HDSLGEESPG KLLRTSVKQE PDSEEEIDSP TKKKSFKSLD TSIFQAEDQF RHPVSSKLEN 180
  181 SELSEVDKPF IASRRSRKPV SY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [203-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AESDEDEDFD DAPTKGSRHK RIVSDDESDD YVEPDHISEA SSEASLPIDE VESMDEDVDG  60
   61 YSDHSVSVAA PIPKKESRKE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [283-1254]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNSLYESYR LGSQIASPSP SVSGSASPTK SNKNGVLNRE EKRRQRMEAF KKENNERYEW  60
   61 LLDVRDADQN RVGDPNYDPR TLYIPPSAWA TFKPFEKQFW KIKKDLMDTV VFFQKGKFYE 120
  121 LYENDAAIGH QVFSLKLTDR VNMKMVGIPE ASFDYWASQF IAKGYRIARV DQLETALGKE 180
  181 IKDRQRTQKE EKVVQRGLTQ VLTSGTLVDE AMLTSDLSTY CMAIKESLQS DNEEPSFGIC 240
  241 FIDTSTGGFH MCEFTDDIHR TKLDTLLTQV RPKELILEKS KISQKSIRAI KYCVSSSSIW 300
  301 NFIKPYTEFW DNERVEREII AGDYFKNGLE GAPKILKSYL SEKPLAISAF GALFWYLRQL 360
  361 KLDKDMCSMG NFDEYDASQQ STSLLMNGQT LKNLEIFSNS FDGGSEGTLF HLLCRCVTPF 420
  421 GKRLFHTWLC HPLRSGTAIN ARLDVVELIA DNPVIRDTIW GFLHKLPDLE RLISRVHAGR 480
  481 SKPADFVRVL EGFQRINSAF DQLREEFMEV AEGTLLGEII QSAPNMKEEL EAWTRAFNWQ 540
  541 KASEEGVFEP EIGFEAEYDT SQKYQSELKN ELYALLEQYK KQLRCSSLNF KNIGKEVYQV 600
  601 EVPSDVKVPV NWCKMSGTKK TNRYYNDELR KKIKKLLEAE ELHLAIMSRM QEKFYIRFDS 660
  661 NYEQWLALIK YTASIDCFFS LSQAAAALGE PYCRPEIIEQ KDGHLYFEEL RHPCINASAA 720
  721 STFVPNDVVL GGESPNMIVL TGPNMAGKST LLRQVCIAVI MAQLGCWVPA KRASITPMTS 780
  781 IYTRLGANDD IMSARSTFMV ELSETKKILD ECGPKSLVIL DELGRGTSTY DGHAIAYAVL 840
  841 HHLVSNIGCL GFFSTHYQSL CVDFMHHRQV RLMQMAAAVD EKIRRVTFLY KLEDGICPKS 900
  901 YGMNVASMAG LPEKVIDAAE EKASELEQAS ASFINASDDI ALMSDFLQVL RISKSIEPLT 960
  961 AVNIPLILDS FE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2o8bB
Description:	No description for 2o8bB was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits