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Protein Overview: SPAP27G11.09c

General Information:
Name(s) found: SPAP27G11.09c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • GTP cyclohydrolase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 326 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: riboflavin biosynthetic process [ISSLink to PubMed article]
    Molecular Function: GTP binding [IEA]
    GTP cyclohydrolase II activity [ISSLink to PubMed article]
    cyclohydrolase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKKEGDQVH HDKTLLQDLS LPENVASEKR LPIDDVQCVN SPMLSPALDI EPKPNVVGTA  60
   61 ERLPKVRCVV RARIPTVKGT EIFLHLYKND FDNKEHLAIV FGQQIRSDSL DAVQEGETEM 120
  121 DRMVRGAYVG TLYPGRKSSY IDVNSSKTTE EQKEEARKTN FVPLVRIHSE CYTGETAWSA 180
  181 RCDCGEQLDE AARLISEEGN GVIIYLRQEG RGIGLSEKLK AYNLQDLGND TVQANLLLQH 240
  241 PADGRSYAVA TAMLMDLGQR DIRLLTNNPE KVNSIEGPNK EVRVVERISM IPKSWRGEKG 300
  301 IESAEVVLYL KTKIEKMGHL LDLPDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] PSI-BLAST 29.69897 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
    2 View Details [128..326] PSI-BLAST 70.221849 Crystal Structure of E. coli GTP cyclohydrolase II in complex with GTP analogue, GMPcPP, and Zinc

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
    		•  4.65541192907612 bayes_pls_golite062009
  • GTP cyclohydrolase activity
    		•  2.51581618679202 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  1.92717548101547 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  1.48770406828775 bayes_pls_golite062009
  • binding
    		•  0.493784774372788 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.464084919475651 bayes_pls_golite062009
  • catalytic activity
    		•  0.343636936190038 bayes_pls_golite062009
  • DNA binding
    		•  0.13720231195318 bayes_pls_golite062009
    2
    Term Confidence Notes
  • GTP cyclohydrolase activity
    		•  4.36867535385235 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  3.7708397651039 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  3.33696578638249 bayes_pls_golite062009
  • catalytic activity
    		•  1.40764037338379 bayes_pls_golite062009
  • binding
    		•  0.769835316275102 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle