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Protein Overview: SPAC637.09

General Information:
Name(s) found: SPAC637.09 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • ribonuclease H70 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 623 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: RNA processing [ISSLink to PubMed article]
    Molecular Function: 3'-5' exonuclease activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGELQDGITQ EDSIEKKSKN VASHGEKRKV KRKKEDLSMD GSNDGVKDSP DSNDDSQSKK  60
   61 KKKKKLKKSQ QPLNEENYPR LQTTENNLQK PLKISDLQEL VFWCLADGQA PSWVLVRNKQ 120
  121 MIHRAVILLV PGLEPSQFGF QPVRGNKHSF LLPNLLNENG PIQLPDFCEV FDRAWPTRSP 180
  181 GDRFRVFSPV NAFLQSPLSN EQKKKRDKET RAMASFSKPS DYLMSYESFI EDEYPLHPTV 240
  241 MKGEEVTQPS GWVASAGDFH SPPINPKILA IDCEMVRTEN GLEIARVTIV DMKSEVIYDE 300
  301 FVKPESPVTD YVTQYSGITE EKLRNVTTVL SDVQSYLKKT VDNNTVLLGH SLNSDLNCLK 360
  361 FTHPHIIDTA NIYNHTRGPP SKPSLKWLAT KWLRREIQKA GALGHDSAED ALACVDLLKL 420
  421 KVKNGPAFGL FNQDFESIFH RLSRQQPTPL IGAIADYGNP ESCIGKAAHK SVSCANDDEV 480
  481 VSAVVSLSDM HNFVWGRFRE LEHAAMWNAN RNTKQENNSD TDTENDSVEE DQVTSYSSAL 540
  541 ERFNRRIRLL YDSLPKGSLL LLYTGTGNPI EMSKLNAIRQ QFRKEYQTKK WDELSVKWTD 600
  601 EENMKYISAV ENTRNGLSFM TIK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..261] deduced N/A No confident structure predictions are available.
    2 View Details [262..350] PSI-BLAST 27.045757 human ISG20
    3 View Details [351..623] PSI-BLAST 4.154902 Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle