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Protein Overview: SPBC15C4.03

General Information:
Name(s) found: SPBC15C4.03 [Sanger Pombe]
Description(s) found:
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  • pir||T39473 probable geranylgeranyl-transferase component, GDP dissociation inhibitor - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582339|sp|O60112.1|YG63_SCHPO RecName: Full=Uncharacterized Rab geranylgeranyltransferase C15C4.03 [NCBI NR]
  • gi|3116146|emb|CAA18894.1| Rab geranylgeranyltransferase escort protein (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112715|ref|NP_595923.1| Rab geranylgeranyltransferase escort protein (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • Rab geranylgeranyltransferase escort protein [Sanger Pombe]
  • Uncharacterized Rab geranylgeranyltransferase C15C4.03 OS=Schizosaccharomyces pombe GN=SPBC15C4.03 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE RAB GERANYLGERANYL-TRANSFERASE ESCORT PROTEIN (REP), GDP DISSOCIATION INHIBITOR: O60112; [pompepVF.fasta]
  • Putative RAB geranylgeranyl-transferase escort protein (REP), GDP dissociation inhibitor [pompep4896]
  • |||putative RAB geranylgeranyl-transferase escort protein (REP), GDP dissociation inhibitor [pompepnew.fasta]
  • SPBC15C4.03 protein [4896.FASTAC]
  • |||RAB geranylgeranyl-transferase escort protein (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative RAB geranylgeranyl-transferase escort protein (REP), GDP dissociation inhibitor [Schizosaccharomyces pombe]gi|3116146|emb|CAA18894.1| SPBC15C4.03 [Schizosaccharomyces pombe]gi|7492589|pir||T39473 probable geranylgeranyl-transferase component, G [nrdb_11152004_Chlamydomonas]
  • |||RAB geranylgeranyl-transferase escort protein |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O60112) Putative RAB geranylgeranyl-transferase escort protein (REP), GDP dissociation inhibitor [pompep4896_normal_reversed]
  • |||Rab geranylgeranyltransferase escort protein |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC15C4.03 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC15C4.03 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • ||rep1|Rab geranylgeranyltransferase escort protein |Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Uncharacterized Rab geranylgeranyltransferase C15C4.03 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC15C4.03 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 459 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: small GTPase mediated signal transduction [ISS]
    regulation of GTPase activity [IEA]
    intracellular protein transport [IEA]
    Molecular Function: GDP-dissociation inhibitor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDPNSYDVI IVGTNLRNSI LSAALSWANQ RVLHIDENSF YGEIDGSLTL RDLEQINEKI  60
   61 KKVDSSQILN DNGSHKSPLK RFEVQFLNKD LIPKNKGSVI QFHPQEIFAS SELVKLLSET 120
  121 KIYKYLLLKP ARSFRLLTSN EEWIKVPESR ADIFNNKNLS LASKRIVMRF MKFVSNIADE 180
  181 QNQNLVKEWE SKPFYKFLEE VFQLSGAIEE SIIYGLCQSL SKDIPTKDAL DTVLKYFHSF 240
  241 GMYGDYSYLL AMYGTGSELC QGFCRSSAVM GGTFMLGQAI DKIDESKIVL KDGSTLSAKK 300
  301 IVSSVDEGKL PHQQIQQRYL LVKGDCQQLF QEDGFFAALD ASLIHFSPFS ISENFGNSVQ 360
  361 AKLYGSGSGD CPEGYCIWYL KTLNDSPCNE VFNLATKKLC SFSGCDDLEI IVQVDETLNQ 420
  421 LRHIDYDDTL HSAKSLFYEI LGQNNTFLQR EGLFDEDDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..459] PSI-BLAST 169.0 Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small GTPase regulator activity
    		•  1.82777033221452 bayes_pls_golite062009
  • binding
    		•  1.71679209220564 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.69589677829425 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.67690582043816 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.00883251592654 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.602525263475244 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.435947245962802 bayes_pls_golite062009
  • DNA binding
    		•  0.390557138920256 bayes_pls_golite062009
  • GDP-dissociation inhibitor activity
    		•  0.387378304822822 bayes_pls_golite062009
  • protein binding
    		•  0.347133050347128 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle