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View Structure Prediction Details

Protein: SPBC15C4.03
Organism: Schizosaccharomyces pombe
Length: 459 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC15C4.03.

Description E-value Query
Range
Subject
Range
gi|47229096 - gi|47229096|emb|CAG03848.1| unnamed protein product [Tetraodon nigroviridis]
590.0 [0..1] [459..1]
gi|114629263 - gi|114629263|ref|XP_507638.2| PREDICTED: GDP dissociation inhibitor 2 [Pan troglodytes]
589.0 [0..5] [457..309]
gi|34810749 - gi|34810749|pdb|1LV0|A Chain A, Crystal Structure Of The Rab Effector Guanine Nucleotide Dissociatio...
588.0 [0..1] [459..3]
gi|396431 - gi|396431|emb|CAA52413.1| rab GDI alpha [Rattus norvegicus]
587.0 [0..1] [459..1]
gi|74150721 - gi|74150721|dbj|BAE25494.1| unnamed protein product [Mus musculus]
586.0 [0..5] [457..70]
gi|3420726, gi|4... - gi|45384364|ref|NP_990335.1| GDP dissociation inhibitor 2 [Gallus gallus], gi|3420726|gb|AAC31910.1|...
586.0 [0..5] [459..3]

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Predicted Domain #1
Region A:
Residues: [1-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDPNSYDVI IVGTNLRNSI LSAALSWANQ RVLHIDENSF YGEIDGSLTL RDLEQINEKI  60
   61 KKVDSSQILN DNGSHKSPLK RFEVQFLNKD LIPKNKGSVI QFHPQEIFAS SELVKLLSET 120
  121 KIYKYLLLKP ARSFRLLTSN EEWIKVPESR ADIFNNKNLS LASKRIVMRF MKFVSNIADE 180
  181 QNQNLVKEWE SKPFYKFLEE VFQLSGAIEE SIIYGLCQSL SKDIPTKDAL DTVLKYFHSF 240
  241 GMYGDYSYLL AMYGTGSELC QGFCRSSAVM GGTFMLGQAI DKIDESKIVL KDGSTLSAKK 300
  301 IVSSVDEGKL PHQQIQQRYL LVKGDCQQLF QEDGFFAALD ASLIHFSPFS ISENFGNSVQ 360
  361 AKLYGSGSGD CPEGYCIWYL KTLNDSPCNE VFNLATKKLC SFSGCDDLEI IVQVDETLNQ 420
  421 LRHIDYDDTL HSAKSLFYEI LGQNNTFLQR EGLFDEDDE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 169.0
Match: 1lv0A
Description: Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small GTPase regulator activity 1.82777033221452 bayes_pls_golite062009
binding 1.71679209220564 bayes_pls_golite062009
GTPase regulator activity 1.69589677829425 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.67690582043816 bayes_pls_golite062009
enzyme regulator activity 1.00883251592654 bayes_pls_golite062009
transcription regulator activity 0.602525263475244 bayes_pls_golite062009
nucleic acid binding 0.435947245962802 bayes_pls_golite062009
DNA binding 0.390557138920256 bayes_pls_golite062009
GDP-dissociation inhibitor activity 0.387378304822822 bayes_pls_golite062009
protein binding 0.347133050347128 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle