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Protein Overview: rga6

General Information:
Name(s) found: rga6 / SPBC354.13 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • GTPase activating protein Rga6 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 733 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: regulation of Rho GTPase activity [ISS]
    Molecular Function: Rho GTPase activator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLNPSTLNN GTLGDLKEHK DVVLSSNAQT DEKRFEEPSL EVGGSLAKVE NGLSTSISSS  60
   61 ASNLEGQQAP FFTKQNSCLS RFRELAQTYN IHEINLEEYV SQIKEVKQSL YSDDSVFNES 120
  121 KSSSPPDAHT DKYFTPCGSP TKLIHSTLLE ERDTPSSLEH VSFYLQESAV SEVRFDKPSN 180
  181 NGPLGRSSLN LSSLSHELQT SQDSPSLSAT NQLSSSDTLE PLQYPPSSFG SQRQFNASQD 240
  241 SPKRSPSKGS WSSILRRPSL TYSPKRQSTG LHRRSLTNYF KFPHRNAHQH NAIAHNPSVF 300
  301 GKPIGDLTSD PTNLCKFTFP TPECAPPSLL LPHIFAQCVH FLSLNALHVP GIFRISGSGP 360
  361 VIKAITEYFY SPPHFWLDET SEIFKRIGFP SYIDIAAVLK RYIMLLPGGL FTHKDILNLL 420
  421 VPLYVDSSRV KVPIDIRNEM AALCFSQIDS YVRFSILCSL LALLHQIATR TQELENGMEN 480
  481 TKDSTLMKPE ALGIIFGPLL LGNSSTDLSK SCPSGNVNDL MRFETEKARV EAKIVEGLII 540
  541 HWPEVLLKIN SLDIPNCFSD VGLTDQVAIF TPAVPKEDSP EQIPENVNAS EESYPNVKHI 600
  601 SKLPLINDSS DNESGNQEND DAVANESTKV VVDNQQPQPK ISTVSDTAVP SMSFANNISS 660
  661 RSVISAATDS KPSTRTSPPF VNNTKPIVAK SPVTVTASSE TNKKSQKINK KASPRVSLWT 720
  721 KLFGKFRSNK KKS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..182] deduced N/A No confident structure predictions are available.
    2 View Details [183..557] PSI-BLAST 49.0 Crystal Structure of the Human Beta2-Chimaerin
    3 View Details [558..733] MSA 3.485997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • Rho GTPase activator activity
    		•  4.25739379139603 bayes_pls_golite062009
  • Rac GTPase activator activity
    		•  4.16341873243208 bayes_pls_golite062009
  • GTPase regulator activity
    		•  2.41361462392252 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.38885756088 bayes_pls_golite062009
  • binding
    		•  1.8899231872471 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  1.79187892586384 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.70400915650397 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.65078918289568 bayes_pls_golite062009
  • protein binding
    		•  1.03543141739589 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  0.769564483290942 bayes_pls_golite062009
  • Ras guanyl-nucleotide exchange factor activity
    		•  0.724386087400895 bayes_pls_golite062009
  • Rho guanyl-nucleotide exchange factor activity
    		•  0.697083262102355 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.423342320468982 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.0257933085345788 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle