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Protein Overview: asp1

General Information:
Name(s) found: asp1 / SPCC1672.06c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • inositol hexakisphosphate kinase/inositol pyrophosphate synthase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 920 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: cortical actin cytoskeleton organization [IMPLink to PubMed article]
    inositol phosphate biosynthetic process [ISS]
    establishment or maintenance of actin cytoskeleton polarity [IMPLink to PubMed article]
    dephosphorylation [IC]
    Molecular Function: ATP binding [IEA]
    inositol hexakisphosphate kinase activity [ISSLink to PubMed article]
    diphosphoinositol-pentakisphosphate kinase activity [IEA]
    inositol hexakisphosphate 4-kinase or 6-kinase activity [ISSLink to PubMed article]
    acid phosphatase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQNASHLTS IDTESSTRTA SPVSSIVTPT KRNVVGICAM DAKARSKPCR NILNRIIAEG  60
   61 EFEAIVFGDN MILDEAVENW PACDYLICFY SSGFPLKKAE KYVELRKPFC VNDVVFQELL 120
  121 WDRRLVLNIL DAIRVSTPQR LICSRDGGPK INKVLEEKLR RKFGIEITEV PTPEVKMLDE 180
  181 DTLSVDGKII KKPYVEKPVY GEDHNIYIYF PKSVGGGGRK LFRKVANKSS DYDPDLCAPR 240
  241 TEGSFIYEEF MNVDNAEDVK VYTVGPHYSH AETRKSPVVD GIVRRNPHGK EIRFITNLSE 300
  301 EEKNMASKIS IAFEQPVCGF DLLRVSGQSY VIDVNGWSFV KDNNDYYDNA ARILKQMFHV 360
  361 AERHRRNRVP SVQEVLNPPP RESEAWRLKS LVGVLRHADR TPKQKFKFSF TSDPFVKLLQ 420
  421 GHTEEVILRN EQLNSVLAAT NLATELKCED INKLKQLRLA LETKKDLPGT KVQLKPAYSP 480
  481 EGKLLKLQLI IKWGGEFTHS ARYQSKDLGE QFHKDLYIMN RDCLKDVEIY TSSERRVSAS 540
  541 AEIFAMAFLE QETIPSDLLK VRKDLLDDSN AAKDTMDKVK KHLKSLLRVG DTARKEFTWP 600
  601 ENMPKPCEVM QQVVQLMKYH RAVMRENFII LGPEVEQVQS RWCCNENPAL FRERWEKLFS 660
  661 EFCDSEKADP SKVSELYDTL KYDALHNRQF LERIFTPYQY LKLPQSPSLI AKEPPQRTDS 720
  721 NGNLVGMTGA NTNHTERPLE KLYELYDLAK VLFDFVSPQE YGIEPKEKLE IGLLTSVPLL 780
  781 RQIIHDIKEA RDSDHASTRM YFTKESHIYT LLNCILESGL PMKLPRNQIP ELDYLTQICF 840
  841 ELFERTNPSG NKEFSVRITL SPGCYAQCPL DMNLDAKHCI SVSPRRSLTR HLDLQQFITK 900
  901 TEDLCNSVHL PKRFIPVNIN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80] MSA 2.053995 View MSA. Confident ab initio structure predictions are available.
    2 View Details [81..370] PSI-BLAST 39.0 STRUCTURE OF GLUTATHIONE SYNTHETASE COMPLEXED WITH ADP AND GLUTATHIONE
    3 View Details [371..920] FFAS03 2.32 THREE-DIMENSIONAL STRUCTURE OF RAT ACID PHOSPHATASE IN COMPLEX WITH L(+) TARTRATE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  2.5009559386228 bayes_pls_golite062009
  • ligase activity
    		•  2.15409885945916 bayes_pls_golite062009
  • binding
    		•  1.06487720097773 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  0.351267830197198 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.239594107637156 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  0.185924207432397 bayes_pls_golite062009
  • protein binding
    		•  0.129820583436109 bayes_pls_golite062009
    3
    Term Confidence Notes
  • phosphofructokinase activity
    		•  2.28979735010509 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  1.80452451925368 bayes_pls_golite062009
  • fructose-2,6-bisphosphate 2-phosphatase activity
    		•  1.77576883882876 bayes_pls_golite062009
  • 6-phosphofructo-2-kinase activity
    		•  1.6353294868526 bayes_pls_golite062009
  • binding
    		•  1.40656644740165 bayes_pls_golite062009
  • phosphoglycerate mutase activity
    		•  1.35261802349721 bayes_pls_golite062009
  • catalytic activity
    		•  1.28113376252793 bayes_pls_golite062009
  • carbohydrate phosphatase activity
    		•  1.2060983846755 bayes_pls_golite062009
  • protein binding
    		•  0.468573500055224 bayes_pls_golite062009
  • intramolecular transferase activity, phosphotransferases
    		•  0.263967875813982 bayes_pls_golite062009
  • isomerase activity
    		•  0.158477745219859 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle