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Protein Overview: SPCC18B5.05c

General Information:
Name(s) found: SPCC18B5.05c [Sanger Pombe]
Description(s) found:
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  • pir||T41198 probable thiamin biosynthesis protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74625845|sp|Q9USL6.1|YJK5_SCHPO RecName: Full=Putative phosphomethylpyrimidine kinase C18B5.05c [NCBI NR]
  • gi|5701960|emb|CAB52152.1| phosphomethylpyrimidine kinase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075435|ref|NP_587935.1| phosphomethylpyrimidine kinase (predicted) [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • phosphomethylpyrimidine kinase [Sanger Pombe]
  • Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase C18B5.05c OS=Schizosaccharomyces pombe GN=SPCC18B5.05c PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE THIAMINE BIOSYNTHESIS PROTEIN: Q9USL6; [pompepVF.fasta]
  • PUTATIVE THIAMINE BIOSYNTHESIS PROTEIN.: ;N0ACC; [pompepV13]
  • Putative thiamine biosynthesis protein [pompep4896]
  • |||putative thiamine biosynthesis protein [pompepnew.fasta]
  • SPCC18B5.05c protein [4896.FASTAC]
  • |||pyrimidine kinase (predicted)|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • putative thiamine biosynthesis protein. [Schizosaccharomyces pombe]gi|5701960|emb|CAB52152.1| SPCC18B5.05c [Schizosaccharomyces pombe]gi|7493028|pir||T41198 probable thiamin biosynthesis protein - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||pyrimidine kinase |Schizosaccharomyces pombe|chr 3|||Manual [pompep2242005.fasta]
  • (Q9USL6) Putative thiamine biosynthesis protein [pompep4896_normal_reversed]
  • |||phosphomethylpyrimidine kinase |Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPCC18B5.05c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPCC18B5.05c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase C18B5.05c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC18B5.05c PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 327 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: phosphorylation [ICLink to PubMed article]
    thiamin biosynthetic process [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    phosphomethylpyrimidine kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEANQSHNAK TNHPTCLTIA GSDCSGAAGI QADLKVMTAH QVYGMSVLTA LTCQNSHGIT  60
   61 GIYPLHPSLI QRQIDACLSD IQCRVVKIGM LPDPKSIPVI SQALTKYKIT DVVMDSVIIS 120
  121 SMGNVMCETP TIPATIQHLF PHLLVYASNV MEAFILVEKT LKKSPPPLKS FPDIQNLMSI 180
  181 IHRLGPKFVV LRGHHVAFDK NMMITEKPDS KSWTADLIYD GKEFYIFEKP YNTTKSIHGE 240
  241 SCSLTAAIAS NLACNIPPLQ AIHEALYSIE WAIQRVHKKS SDPYKSAQLF TALGHSSKFS 300
  301 GSLISLKSEN YIPQADLTSV LLSHIPS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..327] PSI-BLAST 54.0 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphomethylpyrimidine kinase activity
    		•  3.972577109569 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  2.29466565429735 bayes_pls_golite062009
  • kinase activity
    		•  2.28531824242987 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.27980720248925 bayes_pls_golite062009
  • transferase activity
    		•  2.15883296431019 bayes_pls_golite062009
  • catalytic activity
    		•  1.74474587246986 bayes_pls_golite062009
  • hydroxyethylthiazole kinase activity
    		•  1.28568044601242 bayes_pls_golite062009
  • thiamin-phosphate diphosphorylase activity
    		•  1.27602595951972 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  1.12876288824319 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.673555832721854 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.35385659578167 bayes_pls_golite062009
  • binding
    		•  0.2717506679077 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.219913271321955 bayes_pls_golite062009
  • pyridoxal kinase activity
    		•  0.217863391052366 bayes_pls_golite062009
  • DNA binding
    		•  0.101423482181266 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle