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Protein Overview: SPAC343.14c

General Information:
Name(s) found: SPAC343.14c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • translation initiation factor eIF2B [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 393 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    eukaryotic translation initiation factor 2B complex [ISSLink to PubMed article]
    Biological Process: positive regulation of translational initiation [ICLink to PubMed article]
    translational initiation [ISSLink to PubMed article]
    Molecular Function: translation initiation factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTINVEHTY PAVSSLIADL KSRKVQGPFA VAVETALVMR QVISQTRWST VDQLIDTVRA  60
   61 VGSTLVKAQP TEFSCGNIIR RILRLIREEY QELLKTADEN EKLIVSSSNS SSPSQKRDIP 120
  121 SNEKLVQSHE PVSVQMYSSM LNLLGRPTLE SPTHSKTVGD SRVTGGMDMR AVIISGIQDV 180
  181 IDELDKINTD IEVQSMDHLH SNEIILTQGC SKTVEAFLRF AAKKRKFSVI VAEGFPNNQK 240
  241 GSHAMAKRLA QAGIDTTVIS DATIFAIMSR VNKVILGTHA ILGNGGLVTY SGAQLVAQAA 300
  301 RHHATPVVVC SGIYKLSPVY PYDLESIIQL SSPDKIMSFN EGDLISRAEI LNPYYDYIPP 360
  361 DLVDLFITNL GGYPPSYLYR IMNDTYDASD TIL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..393] PSI-BLAST 85.69897 X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  10.1099993541596 bayes_pls_golite062009
  • translation regulator activity
    		•  5.74669335554405 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.59417666488978 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.33012034442687 bayes_pls_golite062009
  • catalytic activity
    		•  1.31732715713197 bayes_pls_golite062009
  • binding
    		•  1.10975674943726 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.09424756417577 bayes_pls_golite062009
  • DNA binding
    		•  0.963080701021607 bayes_pls_golite062009
  • transcription factor activity
    		•  0.452594482400007 bayes_pls_golite062009
  • CoA-transferase activity
    		•  0.0320953696548698 bayes_pls_golite062009
  • protein binding
    		•  0.0293610121675921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle