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View Structure Prediction Details

Protein: SPAC343.14c
Organism: Schizosaccharomyces pombe
Length: 393 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC343.14c.

Description E-value Query
Range
Subject
Range
EIF2B2 - eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
366.0 [0..2] [393..4]
gi|114653985, gi... - gi|55641071|ref|XP_510071.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes], gi|1146539...
365.0 [0..2] [393..4]
gi|109084338, gi... - gi|109084338|ref|XP_001096586.1| PREDICTED: eukaryotic translation initiation factor 2B, subunit 2 b...
365.0 [0..2] [393..4]
gi|47683035, gi|... - gi|47683035|gb|AAH70506.1| Eukaryotic translation initiation factor 2B, subunit 2 beta [Rattus norve...
362.0 [0..3] [393..5]
EI2BB_MOUSE - Translation initiation factor eIF-2B subunit beta OS=Mus musculus GN=Eif2b2 PE=1 SV=1
362.0 [0..3] [393..5]
EI2BB_BOVIN - Translation initiation factor eIF-2B subunit beta OS=Bos taurus GN=EIF2B2 PE=2 SV=1
360.0 [0..3] [393..5]

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Predicted Domain #1
Region A:
Residues: [1-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTINVEHTY PAVSSLIADL KSRKVQGPFA VAVETALVMR QVISQTRWST VDQLIDTVRA  60
   61 VGSTLVKAQP TEFSCGNIIR RILRLIREEY QELLKTADEN EKLIVSSSNS SSPSQKRDIP 120
  121 SNEKLVQSHE PVSVQMYSSM LNLLGRPTLE SPTHSKTVGD SRVTGGMDMR AVIISGIQDV 180
  181 IDELDKINTD IEVQSMDHLH SNEIILTQGC SKTVEAFLRF AAKKRKFSVI VAEGFPNNQK 240
  241 GSHAMAKRLA QAGIDTTVIS DATIFAIMSR VNKVILGTHA ILGNGGLVTY SGAQLVAQAA 300
  301 RHHATPVVVC SGIYKLSPVY PYDLESIIQL SSPDKIMSFN EGDLISRAEI LNPYYDYIPP 360
  361 DLVDLFITNL GGYPPSYLYR IMNDTYDASD TIL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.69897
Match: 1t9kA
Description: X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 10.1099993541596 bayes_pls_golite062009
translation regulator activity 5.74669335554405 bayes_pls_golite062009
nucleic acid binding 1.59417666488978 bayes_pls_golite062009
transcription regulator activity 1.33012034442687 bayes_pls_golite062009
catalytic activity 1.31732715713197 bayes_pls_golite062009
binding 1.10975674943726 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.09424756417577 bayes_pls_golite062009
DNA binding 0.963080701021607 bayes_pls_golite062009
transcription factor activity 0.452594482400007 bayes_pls_golite062009
CoA-transferase activity 0.0320953696548698 bayes_pls_golite062009
protein binding 0.0293610121675921 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle