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Protein Overview: syj2

General Information:
Name(s) found: syj2 / SPBC577.13 [Sanger Pombe]
Description(s) found:
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  • pir||T40557 probable inositol polyphosphate phosphatase family member - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74638872|sp|Q9USQ6.1|SYJ2_SCHPO RecName: Full=Inositol-1,4,5-trisphosphate 5-phosphatase 2; AltName: Full=Synaptojanin-like protein 2 [NCBI NR]
  • gi|5830513|emb|CAB54821.1| inositol-polyphosphate 5-phosphatase (synaptojanin homolog 2) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112103|ref|NP_595311.1| inositol polyphosphate phosphatase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • inositol-polyphosphate 5-phosphatase (synaptojanin homolog 2) [Sanger Pombe]
  • Inositol-1,4,5-trisphosphate 5-phosphatase 2 OS=Schizosaccharomyces pombe GN=syj2 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE INOSITOL POLYPHOSPHATE PHOSPHATASE FAMILY MEMBER: Q9USQ6; [pompepVF.fasta]
  • Putative inositol polyphosphate phosphatase family member [pompep4896]
  • |||putative inositol polyphosphate phosphatase family member [pompepnew.fasta]
  • SPBC577.13 protein [4896.FASTAC]
  • |||inositol polyphosphate phosphatase|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative inositol polyphosphate phosphatase family member [Schizosaccharomyces pombe]gi|5830513|emb|CAB54821.1| SPBC577.13 [Schizosaccharomyces pombe]gi|7492670|pir||T40557 probable inositol polyphosphate phosphatase family member - fission yeast (Schiz [nrdb_11152004_Chlamydomonas]
  • (Q9USQ6) Putative inositol polyphosphate phosphatase family member [pompep4896_normal_reversed]
  • |syj2||inositol-polyphosphate 5-phosphatase |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC577.13 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • inositol polyphosphate phosphatase [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |syj2||inositol-polyphosphate 5-phosphatase, synaptojanin homolog 2 |Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Inositol-1,4,5-trisphosphate 5-phosphatase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=syj2 PE=2 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 889 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: cellular response to stress [IEPLink to PubMed article]
    phosphatidylinositol metabolic process [ISSLink to PubMed article]
    inositol lipid-mediated signaling [ICLink to PubMed article]
    endocytosis [ISSLink to PubMed article]
    phosphoinositide dephosphorylation [ISSLink to PubMed article]
    Molecular Function: phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [IEA]
    inositol-polyphosphate 5-phosphatase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQCYLKRKER SVAFITEKYA AIIQKPSVKD SDCIITFTCI SLEEFEKIKE YELLFGGEKI  60
   61 LGTLGLFNYV CEDMKEGVFL CVARKAKLVL RIGNRDPISK LENVSFISLD QELWDEELFE 120
  121 PMPRNSSPSS TFSTSTSDLN NIEKDNLVNS EYSSKYSSTT RIYPYHSLSQ LTDLLTDGSF 180
  181 YVSTNISCFS RFQSEQPYGP KDIYCWNRFL ITELDNHFSE AHILEKFPNL LLHCFRGYVE 240
  241 RMFIDSMSMS IISKVSSYGS RQTYPPSGID DSSYCSMFVE TEFIVEIAQT VFSFVQVRGT 300
  301 VPCFWEEQFS SWYGPSISFL RSSQASQSLF NFHFSKLYKA YGDIYVIDLL QTKGFEASLY 360
  361 EAYKHHLMLL PFPAVVKKFH FTPDPARPDI DPRLETDLAD DLKEMGYTQK SIENDMLESF 420
  421 QKGVFRINDL DCLGRTNVIQ YQISRLVLKD IFFNLQIGVT FNILEYLRHL WSNNGDAIAK 480
  481 LITGVGSIGS SATRRGRKSI AGSLSDISKS FGRMYVGRYP DVESQNAILL LLGCFPNQSP 540
  541 VLISESVSSY IQGVLRQRRS EYRVERDFSI FSSTFNANGK VPSTDEFKRL LLPFGERTSA 600
  601 YDLYVVAVQE IITLNMSHLV SSSNQKLRIW EEKILMILNS RDSNNKYMLI SSIQMAGVFL 660
  661 GVFIRKDDHL VVSKVTKTTR KTGFGGFSAN KGAVAIEMNV CDSDFCFVSS HFAPKVNNIS 720
  721 ERNMEYTSIS DNLVFPSGMK IYDHTNILWM GDFNYRIDSD NEEVRKLVEL DDLDKLASYD 780
  781 QLCTEMKKGT VFHGLVEPQL TFLPTYKFDN GTNDYDTSDK QRVPSWTDRI LATKSFTRNC 840
  841 YKSCDIRCSD HRPVFATFSL KIFSTCMDKK AGIIRDARIA YIKSKNSNK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..206] MSA 1.082983 View MSA. No confident structure predictions are available.
    2 View Details [207..354] deduced N/A No confident structure predictions are available.
    3 View Details [355..458] MSA 1.091979 View MSA. No confident structure predictions are available.
    4 View Details [459..545] deduced N/A Confident ab initio structure predictions are available.
    5 View Details [546..889] PSI-BLAST 113.0 Synaptojanin, IPP5C domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle