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Protein Overview: gua2

General Information:
Name(s) found: gua2 / SPAP7G5.02c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • GMP synthase [glutamine-hydrolyzing] [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 539 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: glutamine metabolic process [IEA]
    GMP biosynthetic process [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    GMP synthase (glutamine-hydrolyzing) activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTEVPGEV STSVSSYFDT ILILDFGSQY SHLIARRLRE IHVYAELLPC TQKIEALPFK  60
   61 PIGVILSGGP YSVYDDIAPH VDPAVFELGV PVLGICYGMQ EIAWLNGRCV EPGIEREYGP 120
  121 ATVSMEPEIK TEVFKSFFNS MPKEFEVWMS HGDRLSALPN GYETIGRTKN SPFAVIAHVT 180
  181 KPIIGLQFHP EVTHTPLGLQ LIKNFAIEIC HAKPNWSMEN FVDKEILRIR KMIGPSDHVI 240
  241 GAVSGGVDST VASKVLKEAI GDRFHAIMVD NGLLRLNEAE IVRETLNKHL GIQLTVVDAS 300
  301 EEFIGKLKGV TDPEKKRKII GNTFIHVFER EAERIVKETN GKVEYLLQGT LYPDVIESIS 360
  361 FKGPSQTIKT HHNVGGLLKD MKLKLIEPLR ELFKDEVRAL GELLGIEHSL VWRHPFPGPG 420
  421 LGIRILGEVN AAQLEIARKA DHIFITEIRN HGYYDKISQA FAALLPVKAV GVMGDKRTHE 480
  481 QVIALRAITT SDFMTADWYD GFSIKFLKLV SSRICNEVSG VNRVLYDISS KPPATVEME

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..539] PSI-BLAST 139.0 GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • carbon-nitrogen ligase activity, with glutamine as amido-N-donor
    		•  2.70451256281397 bayes_pls_golite062009
  • anthranilate synthase activity
    		•  2.51214170411838 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.33781404450996 bayes_pls_golite062009
  • phosphoribosylformylglycinamidine synthase activity
    		•  1.83575136996743 bayes_pls_golite062009
  • carbamoyl-phosphate synthase activity
    		•  1.74828881793189 bayes_pls_golite062009
  • carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
    		•  1.74029540439985 bayes_pls_golite062009
  • ligase activity
    		•  1.70348758031146 bayes_pls_golite062009
  • oxo-acid-lyase activity
    		•  1.35896725827905 bayes_pls_golite062009
  • catalytic activity
    		•  1.30391542469987 bayes_pls_golite062009
  • GMP synthase activity
    		•  0.413068109408727 bayes_pls_golite062009
  • asparagine synthase (glutamine-hydrolyzing) activity
    		•  0.3673193848392 bayes_pls_golite062009
  • imidazoleglycerol-phosphate synthase activity
    		•  0.270391651600004 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.0769356405014503 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle