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Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the reaction: ATP + xanthosine 5'-phosphate + NH3 = AMP + diphosphate + GMP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: GMP synthase activity
Acc: GO:0003921
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + xanthosine 5'-phosphate + NH3 = AMP + diphosphate + GMP.
Synonyms:
  • xanthosine-5'-phosphate-ammonia ligase activity
  • XMP aminase activity
  • guanylate synthetase activity
  • xanthosine 5'-monophosphate aminase activity
  • Xanthosine-5'-phosphate--ammonia ligase activity
  • xanthosine-5'-phosphate:ammonia ligase (AMP-forming)
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003921 - GMP synthase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle