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Protein Overview: SPBC23E6.10c

General Information:
Name(s) found: SPBC23E6.10c [Sanger Pombe]
Description(s) found:
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  • pir||T39944 hypothetical translation initiation factor - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582365|sp|O60185.1|MTNA_SCHPO RecName: Full=Methylthioribose-1-phosphate isomerase; Short=MTR-1-P isomerase; Short=M1Pi; AltName: Full=S-methyl-5-thioribose-1-phosphate isomerase; AltName: Full=Translation initiation factor eIF-2B subunit alpha/beta/ [NCBI NR]
  • gi|3116128|emb|CAA18878.1| methylthioribose-1-phosphate isomerase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113402|ref|NP_596610.1| methylthioribose-1-phosphate isomerase (predicted) (PMID 15215245) [Schizosaccharomyces pombe] [NCBI NR]
  • methylthioribose-1-phosphate isomerase [Sanger Pombe]
  • Methylthioribose-1-phosphate isomerase OS=Schizosaccharomyces pombe GN=mri1 PE=2 SV=1 [Swiss-Prot]
  • Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein OS=Schizosaccharomyces pombe GN=SPBC23E6.10c PE=2 SV=1 [Swiss-Prot]
  • TRANSLATION INITIATION FACTOR EIF-2 FAMILY: O60185; [pompepVF.fasta]
  • Putative translation initiation factor eif-2 family [pompep4896]
  • |||putative translation initiation factor eif-2 family [pompepnew.fasta]
  • SPBC23E6.10c protein [4896.FASTAC]
  • |||translation initiation factor|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • translation initiation factor eif-2 family [Schizosaccharomyces pombe]gi|3116128|emb|CAA18878.1| SPBC23E6.10c [Schizosaccharomyces pombe]gi|7492051|pir||T39944 hypothetical translation initiation factor - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||methylthioribose-1-phosphate isomerase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O60185) Putative translation initiation factor eif-2 family [pompep4896_normal_reversed]
  • hypothetical protein SPBC23E6.10c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC23E6.10c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Methylthioribose-1-phosphate isomerase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mri1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 359 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: L-methionine salvage from methylthioadenosine [ISSLink to PubMed article]
    Molecular Function: S-methyl-5-thioribose-1-phosphate isomerase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLQAIIYNE DKLLVLDQLL LPYERKYISV SNVEDAFAVI KKMQVRGAPA IAIVAALSVA  60
   61 VGLKHLSEDA DAKEYVINSF EHLKQSRPTA VNLFETAKFM QGIALQEGKN CRNKIIQEAE 120
  121 RMLVKDLEDN HNIGTAGRKF LLQHYKDKDK LTVLTHCNTG SLATSGYGTA LGIIRSLHES 180
  181 GNLEHAYCTE TRPYNQGSRL TAFELVHDKI PATLVTDSTV ASIMHKIDAI VVGADRVTRN 240
  241 GDTANKIGTY NLAILAKHFG KPFIVAAPFS SIDTSLASGS QITIEQRPPI EMTTITGPII 300
  301 TDSNSRNLED PKRVRISIAA PGIDVYSPAF DVTPANLITA IATEKGFYTQ QTNNKYDFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..359] PSI-BLAST 112.0 X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  10.1099993541596 bayes_pls_golite062009
  • translation regulator activity
    		•  5.74669335554405 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.17718456512191 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.9283980201455 bayes_pls_golite062009
  • DNA binding
    		•  1.55389679363348 bayes_pls_golite062009
  • binding
    		•  1.53908996868286 bayes_pls_golite062009
  • transferase activity, transferring sulfur-containing groups
    		•  1.40526340076289 bayes_pls_golite062009
  • catalytic activity
    		•  1.31732715713197 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.09424756417577 bayes_pls_golite062009
  • transcription factor activity
    		•  0.995059566132783 bayes_pls_golite062009
  • deaminase activity
    		•  0.518630450774121 bayes_pls_golite062009
  • S-methyl-5-thioribose-1-phosphate isomerase activity
    		•  0.511292518421556 bayes_pls_golite062009
  • protein binding
    		•  0.0293610121675921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle