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Protein Overview: sst2

General Information:
Name(s) found: sst2 / SPAC19B12.10 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • human AMSH protein homolog [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 435 amino acids

    Gene Ontology:
    Cellular Component: endosome [NASLink to PubMed article]
    Biological Process: protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway [IMPLink to PubMed article]
    late endosome to vacuole transport [IMPLink to PubMed article]
    Molecular Function: ubiquitin thiolesterase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNILQGSEAP LSYEEIASRA GAFDFNKNIP LKNWLRTSTT ISKQAHVYVS EHDYSNGVFL  60
   61 LFRYCELFMK CQKHPDAAAY KKELFDYYQG VRNALEEIEL IKPIVKEQYE QYQCQKNDLD 120
  121 DLKKLSMKDS QPSLEKPVSY VDEPILEQWA LSDLQILPPS STDLLSPDSQ KLSKSSSDLP 180
  181 QFDYPSLNSS PTFNSNLPIS SSRFEKTSLS DSKLVSPEPL DDNKDIQFIK KPIYTRTSEP 240
  241 RPKPAGTFKI HAYTEGGKPL RTIYLPKLLK KVFLDVVKPN TKKNLETCGI LCGKLRQNAF 300
  301 FITHLVIPLQ EATSDTCGTT DEASLFEFQD KHNLLTLGWI HTHPTQTCFM SSVDLHTHCS 360
  361 YQLMLPEAIA IVMAPSKNTS GIFRLLDPEG LQTIVKCRKP GLFHPHEGKV YTMVAQPGHV 420
  421 REINSKLQVV DLRVK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..167] PSI-BLAST 19.39794 Structure of the N-terminal domain of Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8)
    2 View Details [168..243] deduced N/A No confident structure predictions are available.
    3 View Details [244..435] PSI-BLAST 24.69897 No description for 2p87A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle