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Protein Overview: dic1

General Information:
Name(s) found: dic1 / SPBC646.17c [Sanger Pombe]
Description(s) found:
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  • gi|9716239|emb|CAC01482.1| SPBC646.17c [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112168|ref|NP_595375.1| hypothetical protein SPBC855.01c [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|162312168|ref|XP_001713125.1| dynein intermediate chain Dic1 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|157310398|emb|CAA22821.2| dynein intermediate chain Dic1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|156630497|sp|O94518.2|DIC1_SCHPO RecName: Full=Dynein intermediate chain 1; AltName: Full=Meiotically up-regulated gene 44 protein [NCBI NR]
  • dynein intermediate chain Dic1 [Sanger Pombe]
  • Dynein intermediate chain 1 OS=Schizosaccharomyces pombe GN=dic1 PE=1 SV=2 [Swiss-Prot]
  • WD REPEAT PROTEIN; NO APPARENT S. CEREVISIAE ORTHOLOG: O94518;Q9HGZ7;Q9P7A2; [pompepVF.fasta]
  • PUTATIVE CYTOPLASMIC DYNEIN INTERMEDIATE CHAIN; WD REPEAT PROTEIN CYTOPLASMIC DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN INTERMEDIATE CHAIN; WD REPEAT PROTEIN: O94518;Q9HGZ7;Q9P7A2; [pompepV13]
  • Cytoplasmic dynein intermediate chain [pompep4896]
  • ||SPBC855.01c, SPBP35G2.01c|WD repeat protein [pompepnew.fasta]
  • SPBC855.01c protein (Spbc646.17c protein) (Spbp35g2.01c protein) [4896.FASTAC]
  • ||SPBC855.01c, SPBP35G2.01c|WD repeat protein|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • cytoplasmic dynein intermediate chain [Schizosaccharomyces pombe]gi|9716239|emb|CAC01482.1| SPBC855.01c [Schizosaccharomyces pombe] [nrdb_11152004_Chlamydomonas]
  • (Q9HGZ7) Cytoplasmic dynein intermediate chain [pompep4896_normal_reversed]
  • |dic1|SPBC855.01c, SPBP35G2.01c, mug44|dynein intermediate chain Dic1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC646.17c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Dynein intermediate chain 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dic1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 544 amino acids

    Gene Ontology:
    Cellular Component: dynein complex [TASLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: ascospore formation [IMPLink to PubMed article]
    dynein-driven meiotic oscillatory nuclear movement [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKNIKREIE IKRAKLLLLK NKENCTDAVS SSNKEGPKQI SEDQLSNFLC KILKPTNLTP  60
   61 QTYSLESKSS NLVSDCELKI SSVYQSYSST FNVSNHVPSI SKTVNIRETS KHLKHSTKAP 120
  121 KCSLPTSALE IDHLNNFLHS SAKILDRALC DQSNQLFTDY TVKKKSKKNK SQLEENGLNH 180
  181 LFTFQDEKIT LNSVVNSISY SSFFEELLIT SYAKPKEALR TRGLAIVWNQ RWKNSPESVL 240
  241 KARSEITVCK PSPFHPQLIA GGAYNGQVFL WDLRQGQYPV SFTTIISGGH LEPVTDITYI 300
  301 NNPPSNNIVT CSTDGLVHIW EPDMFSRPSE TICLSSQVDS SSQCIPATCL SFIPENNMEF 360
  361 LVGAEDGKLQ RGYRSDYSET KAVQPSNVSY EGHNVFISGI DVMTSNSQNV FLEKNKDFAL 420
  421 TSSFDWTVRL WQCSPSRNQH ELVPSNDLDE QVIINSCKTF THKAMVFDVK WCVSEPCCFA 480
  481 SVDALGNLNL WDLQKDVEAP VTSDIPDGKP LNKIAWQPEK RNLACGGLNG NVHIYKHLSP 540
  541 NLAN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..544] PSI-BLAST 29.69897 Actin interacting protein 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • actin binding
    		•  2.27900251096697 bayes_pls_golite062009
  • binding
    		•  1.8484919978091 bayes_pls_golite062009
  • dynein binding
    		•  1.73730057055973 bayes_pls_golite062009
  • protein binding
    		•  1.24173112731149 bayes_pls_golite062009
  • dynein heavy chain binding
    		•  0.894931976836991 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.707581908546932 bayes_pls_golite062009
  • transporter activity
    		•  0.692270256454453 bayes_pls_golite062009
  • actin filament binding
    		•  0.554537899540618 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.121183207943714 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle