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Protein Overview: ams1

General Information:
Name(s) found: ams1 / SPAC513.05 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • alpha-mannosidase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1077 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: mannose metabolic process [IEA]
    oligosaccharide catabolic process [ISSLink to PubMed article]
    Molecular Function: alpha-mannosidase activity [ISSLink to PubMed article]
    zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLFPVLNNT PVGKQVDSIY ESRLDQFLSE GQYRDFNLPS VYDHARIDNP SGDVNNDLSK  60
   61 GFVDLKVYRV PDLSRPSFNE VVGHKKFDET ASKGDTFGPS WATFWFEVHI RLPKSWAKYE 120
  121 QVIFQWNCDN EGLVYSQDGV PLQAFSGSER TDFILPDSWK TTEDTFYIEM ACNGMFGTGA 180
  181 GSQIAPPDPN RYFTLTKADL VAPNLPAMAL AYDFLLMQQC VKQLPSNCWQ KYKARQICND 240
  241 IMNTFHPNDL STINECRNLA KAFLGNDIDS EAVFEKNNDK ANVFAIGHCH IDTAWLWPFA 300
  301 ETRRKIVRSW ATQMNIMDRY PEYQFVCSQA LQYLWLKEDH PDVFEKLKEY VNQNKFIPIG 360
  361 GSWVEHDTNI PNGESLIRQF LLGQHFFEKE FGVRCRTFWL PDTFGYSSQI PQICRLCGMD 420
  421 RFLTQKLSWN NINSFPTSTF NWVALDGSQV ICHMPPANTY TADTNVNDVL HSIDQHKNLV 480
  481 NDQAGLLVFG IGDGGGGPTP EMLEKLRRCK GIANTVGYLP NVKLGNTVDE FFDGILKRTN 540
  541 AGQTLPSWNG ELYFEFHRGT YTTQAELKKL MRKVEIALHD AEYVSTLASI FSKDYSYPKE 600
  601 SLQDLWRDTL LCQFHDVLPG SCIEMVYKDA IPIMSKVLKN TEALLWQAIE QLGFKKASSS 660
  661 DNKEQLCLLN TLPWNVRGVI TETEENKLVY FESCDGKGIL TAAHTSLKHP AAAYQKDDNF 720
  721 ILVNDHLRVT IAPNGLILSL FDLHKEREIL DLKSGKNHAG ANQYVLFEDT PLSWQAWDTE 780
  781 VFSLEKYEVL DKGKVSIKES GPLRASVVVD IPISELSHMK ATISLEGYND CSEFTGVNFT 840
  841 CEVDWHESCK FLKVEFPVDI HSEFASYETQ FGITKRPTHY NTSWDVAKFE VCHQKFADYS 900
  901 DFTYGVSVLN DCKYGFSTHG NLMRLSLLRS PKQPDAHADM GKHTIRYAVY PHSKPLDSST 960
  961 VRAAHKFNSN FRLLTRASDT ANLDIFDAFQ LVGEPNVILS HIKMAEKGKS IILRVYESLG1020
 1021 GKSRARLVIK SLTVASVTKC NGLEEDLEEL CTLKSNDYYE VPIELRAFEI ATFKVNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] MSA 1.074993 View MSA. No confident structure predictions are available.
    2 View Details [100..249] MSA 1.102976 View MSA. No confident structure predictions are available.
    3 View Details [250..986] PSI-BLAST 156.0 Golgi alpha-mannosidase II in complex with kifunensine
    4 View Details [987..1077] PSI-BLAST 8.09691 The structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low pH activation


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle