YRC Public Data Repository - Protein Structure Prediction

Protein:	ams1
Organism:	Schizosaccharomyces pombe
Length:	1077 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ams1.

Description	E-value	Query Range	Subject Range
gi\|145011432, gi... - gi\|39944964\|ref\|XP_362019.1\| hypothetical protein MGG_04464 [Magnaporthe grisea 70-15], gb\|EAA50705....	1113.0	[0..1]	[1077..12]
gi\|42553194, gi\|... - gi\|46124907\|ref\|XP_387007.1\| hypothetical protein FG06831.1 [Gibberella zeae PH-1], gi\|42553194\|gb\|E...	1096.0	[0..2]	[1077..68]
gi\|28919854, gi\|... - gi\|32414421\|ref\|XP_327690.1\| hypothetical protein [Neurospora crassa], gi\|28919854\|gb\|EAA29252.1\| hy... gi\|85090586 - gi\|85090586\|ref\|XP_958488.1\| hypothetical protein NCU07404 [Neurospora crassa OR74A]	1096.0	[0..1]	[1077..12]
gi\|71000154, gi\|... - gi\|71000154\|ref\|XP_754794.1\| alpha-mannosidase [Aspergillus fumigatus Af293], gi\|66852431\|gb\|EAL9275... gi\|159127803 - gi\|159127803\|gb\|EDP52918.1\| alpha-mannosidase [Aspergillus fumigatus A1163]	1063.0	[0..2]	[1077..11]
gi\|169767820 - gi\|169767820\|ref\|XP_001818381.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83766236 - gi\|83766236\|dbj\|BAE56379.1\| unnamed protein product [Aspergillus oryzae]	1060.0	[0..2]	[1077..11]
gi\|57338726 - gi\|57338726\|gb\|AAW49442.1\| mannosidase II [Aspergillus fumigatus]	1060.0	[0..2]	[1077..11]
gi\|119177282, gi... - gi\|90299220\|gb\|EAS28851.1\| hypothetical protein CIMG_07597 [Coccidioides immitis RS], gi\|119177282\|r...	1052.0	[0..2]	[1077..11]
gi\|116180702, gi... - gi\|88185276\|gb\|EAQ92744.1\| hypothetical protein CHGG_00979 [Chaetomium globosum CBS 148.51], gi\|1161...	1047.0	[0..2]	[1077..13]
gi\|40744331, gi\|... - gi\|67524957\|ref\|XP_660540.1\| hypothetical protein AN2936.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	1045.0	[0..2]	[1032..11]

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Predicted Domain #1

Region A:
Residues: [1-99]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLFPVLNNT PVGKQVDSIY ESRLDQFLSE GQYRDFNLPS VYDHARIDNP SGDVNNDLSK  60
   61 GFVDLKVYRV PDLSRPSFNE VVGHKKFDET ASKGDTFGP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [100-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SWATFWFEVH IRLPKSWAKY EQVIFQWNCD NEGLVYSQDG VPLQAFSGSE RTDFILPDSW  60
   61 KTTEDTFYIE MACNGMFGTG AGSQIAPPDP NRYFTLTKAD LVAPNLPAMA LAYDFLLMQQ 120
  121 CVKQLPSNCW QKYKARQICN DIMNTFHPND

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [250-986]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSTINECRNL AKAFLGNDID SEAVFEKNND KANVFAIGHC HIDTAWLWPF AETRRKIVRS  60
   61 WATQMNIMDR YPEYQFVCSQ ALQYLWLKED HPDVFEKLKE YVNQNKFIPI GGSWVEHDTN 120
  121 IPNGESLIRQ FLLGQHFFEK EFGVRCRTFW LPDTFGYSSQ IPQICRLCGM DRFLTQKLSW 180
  181 NNINSFPTST FNWVALDGSQ VICHMPPANT YTADTNVNDV LHSIDQHKNL VNDQAGLLVF 240
  241 GIGDGGGGPT PEMLEKLRRC KGIANTVGYL PNVKLGNTVD EFFDGILKRT NAGQTLPSWN 300
  301 GELYFEFHRG TYTTQAELKK LMRKVEIALH DAEYVSTLAS IFSKDYSYPK ESLQDLWRDT 360
  361 LLCQFHDVLP GSCIEMVYKD AIPIMSKVLK NTEALLWQAI EQLGFKKASS SDNKEQLCLL 420
  421 NTLPWNVRGV ITETEENKLV YFESCDGKGI LTAAHTSLKH PAAAYQKDDN FILVNDHLRV 480
  481 TIAPNGLILS LFDLHKEREI LDLKSGKNHA GANQYVLFED TPLSWQAWDT EVFSLEKYEV 540
  541 LDKGKVSIKE SGPLRASVVV DIPISELSHM KATISLEGYN DCSEFTGVNF TCEVDWHESC 600
  601 KFLKVEFPVD IHSEFASYET QFGITKRPTH YNTSWDVAKF EVCHQKFADY SDFTYGVSVL 660
  661 NDCKYGFSTH GNLMRLSLLR SPKQPDAHAD MGKHTIRYAV YPHSKPLDSS TVRAAHKFNS 720
  721 NFRLLTRASD TANLDIF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	156.0
Match:	1ps3A
Description:	Golgi alpha-mannosidase II in complex with kifunensine
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [987-1077]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAFQLVGEPN VILSHIKMAE KGKSIILRVY ESLGGKSRAR LVIKSLTVAS VTKCNGLEED  60
   61 LEELCTLKSN DYYEVPIELR AFEIATFKVN L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.09691
Match:	1o7dE
Description:	The structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low pH activation
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits