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Protein Overview: sim4

General Information:
Name(s) found: sim4 / SPBC18E5.03c [Sanger Pombe]
Description(s) found:
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  • pir||T39754 hypothetical protein SPBC18E5.03c - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|46396678|sp|O94494.1|SIM4_SCHPO RecName: Full=Centromere protein sim4; AltName: Full=Silencing in the middle of the centromere protein 4 [NCBI NR]
  • gi|4107322|emb|CAA22663.1| kinetochore protein Sim4 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112641|ref|NP_595849.1| kinetochore protein Sim4 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • kinetochore protein Sim4 [Sanger Pombe]
  • Centromere protein sim4 OS=Schizosaccharomyces pombe GN=sim4 PE=1 SV=1 [Swiss-Prot]
  • HYPOTHETICAL PROTEIN; PREDICTED COILED-COIL REGION; SEQUENCE ORPHAN: O94494; [pompepVF.fasta]
  • HYPOTHETICAL PROTEIN; POSSIBLE COILED-COIL REGION; SEQUENCE ORPHAN: O94494; [pompepV13]
  • Hypothetical protein, possible coiled-coil region [pompep4896]
  • |||hypothetical protein [pompepnew.fasta]
  • Centromere protein sim4 (Silencing in the middle of the centromere protein 4) [4896.FASTAC]
  • |sim4||localization centromere|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • hypothetical protein; possible coiled-coil region [Schizosaccharomyces pombe]gi|4107322|emb|CAA22663.1| SPBC18E5.03c [Schizosaccharomyces pombe]gi|46396678|sp|O94494|SIM4_SCHPO Centromere protein sim4 (Silencing in the middle of the centromere protein 4 [nrdb_11152004_Chlamydomonas]
  • |sim4||kinetochore protein Sim4p |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O94494) Hypothetical protein, possible coiled-coil region [pompep4896_normal_reversed]
  • |sim4||kinetochore protein Sim4|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC18E5.03c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC18E5.03c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |sim4||kinetochore protein, CENP-K ortholog, Sim4|Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Centromere protein sim4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sim4 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 277 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article][IDALink to PubMed article]
    inner kinetochore of condensed chromosome [IDALink to PubMed article]
    condensed chromosome, centromeric region [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Mis6-Sim4 complex [TASLink to PubMed article]
    Biological Process: chromatin silencing at centromere [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    kinetochore assembly [TASLink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    CenH3-containing nucleosome assembly at centromere [TASLink to PubMed article]
    cell cycle [RCALink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSENASLFR NILNDTENLV QPLTQDESRL ALFESLVQSD QLLVEKIEKW EKKVSKFTEN  60
   61 SKSEKRKLQL ELFQEIIDLK KCIAFKPIIG KNAIDNNISD LKKNLHSNKK LEAVLKEELH 120
  121 QIKKFSSDLQ SLKSSMGERQ KQQAAMSRRG KKSIIHSAII QEKERYEKES QELFTFLDGF 180
  181 LDEHAPSLLE GAQASIDKNR PGKNQPSLNF ENISKKDLTE EFKQVIENLM NNSIIPGSPY 240
  241 IEVKNERIVS FLVLASLCTV DPQDPSKVKL IPFSDEI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..277] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle