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The formation of nucleosomes containing the histone H3 variant CenH3 (also called CENP-A) to form centromeric chromatin; occurs outside the context of DNA replication. The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. The formation or destruction of chromatin structures, occurring outside the context of DNA replication. Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors. The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. Dynamic structural changes in centromeric DNA. The formation of nucleosomes outside the context of DNA replication. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: CenH3-containing nucleosome assembly at centromere
Acc: GO:0034080
Aspect: Biological Process
Desc: The formation of nucleosomes containing the histone H3 variant CenH3 (also called CENP-A) to form centromeric chromatin; occurs outside the context of DNA replication.
Synonyms:
  • centromere specific nucleosome exchange
  • centromeric DNA replication-independent nucleosome assembly
  • DNA replication-independent nucleosome assembly at centromere
  • centromere-specific nucleosome assembly
  • centromere-specific histone exchange
Proteins in PDR annotated with:
   This term: 10 [Search]
   Term or descendants: 10 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0034080 - CenH3-containing nucleosome assembly at centromere (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle