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Protein Overview: ins1

General Information:
Name(s) found: ins1 / SPCC306.05c [Sanger Pombe]
Description(s) found:
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  • pir||T41283 probable growth response protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74626320|sp|Q9Y7R5.1|INS1_SCHPO RecName: Full=INSIG family protein [NCBI NR]
  • gi|4704280|emb|CAB41653.1| INSIG domain protein [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075313|ref|NP_587813.1| INSIG domain protein [Schizosaccharomyces pombe] [NCBI NR]
  • INSIG domain protein [Sanger Pombe]
  • INSIG family protein OS=Schizosaccharomyces pombe GN=ins1 PE=1 SV=1 [Swiss-Prot]
  • HYPOTHETICAL PROTEIN; SEQUENCE ORPHAN; NO APPARENT S. CEREVISIAE ORTHOLOG: Q9Y7R5; [pompepVF.fasta]
  • POSSIBLE GROWTH RESPONSE PROTEIN; CONTAINS PFAM-B_35059: Q9Y7R5; [pompepV13]
  • Possible growth response protein [pompep4896]
  • |||hypothetical protein [pompepnew.fasta]
  • SPCC306.05c protein [4896.FASTAC]
  • |ins1||INSIG domain|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • possible growth response protein [Schizosaccharomyces pombe]gi|4704280|emb|CAB41653.1| SPCC306.05c [Schizosaccharomyces pombe]gi|7492619|pir||T41283 probable growth response protein - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (Q9Y7R5) Possible growth response protein [pompep4896_normal_reversed]
  • |ins1||INSIG domain protein|Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPCC306.05c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPCC306.05c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • INSIG family protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ins1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 281 amino acids

    Gene Ontology:
    Cellular Component: SREBP-SCAP complex [TASLink to PubMed article]
    integral to membrane [IEA]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: response to hypoxia [TASLink to PubMed article]
    sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway [TASLink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [TASLink to PubMed article]
    positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway [TASLink to PubMed article]
    negative regulation of ergosterol biosynthetic process [IDALink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKEIYEPR PRYPDGYNGN RAVKKSLSVL SLDNMKSTLS GLFAPLKLDE EQAEDDESLS  60
   61 SYEDYASRQI DDDLKKQRKK GITFIDYSSL ITFFCKLCVI FGLGFVFTYL AEQIVQDAKL 120
  121 PLLTVNLKSW KFEPPWPAIF GFVAVILGLS YRRMDTKYPL GAAPLRPSQS SKWQWISRYL 180
  181 AAFATLLLSM KKLLFISNSH SIVALVASSA SIWYIFDRSR NGIILSTITS VLGSILYYNL 240
  241 VDTSKIELNG VEFPEIQFRL WIPMILFSAS TIVGNAGRLL F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] deduced N/A No confident structure predictions are available.
    2 View Details [86..281] Pfam 131.657577 No description for PF07281.3 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle