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Protein Overview: ase1

General Information:
Name(s) found: ase1 / SPAPB1A10.09 [Sanger Pombe]
Description(s) found:
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  • gi|74624468|sp|Q9HDY1.1|ASE1_SCHPO RecName: Full=Anaphase spindle elongation protein 1 [NCBI NR]
  • gi|19114435|ref|NP_593523.1| microtubule-associated protein Ase1 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|12188973|emb|CAC21482.1| antiparallel microtubule cross-linking factor Ase1 [Schizosaccharomyces pombe] [NCBI NR]
  • microtubule-associated protein Ase1 [Sanger Pombe]
  • Anaphase spindle elongation protein 1 OS=Schizosaccharomyces pombe GN=ase1 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE MICROTUBULE-ASSOCIATED PROTEIN; POSSIBLY REQUIRED FOR ANAPHASE SPINDLE ELONGATION; SIMILAR TO S. CEREVISIAE ASE1; SIMILAR TO HUMAN PRC1, PROTEIN REGULATING CYTOKINESIS: Q9HDY1; [pompepVF.fasta]
  • LOW SIMILARITY TO S. CEREVISIAE ASE1, MICROTUBULE-ASSOCIATED PROTEIN REQUIRED FOR ANAPHASE SPINDLE ELONGATION; AND HUMAN PRC1, PROTEIN REGULATING CYTOKINESIS: Q9HDY1; [pompepV13]
  • Low similarity to S. cerevisiae ase1, microtubule-associated protein required for anaphase spindle elongation, and human prc1, protein regulating cytokinesis [pompep4896]
  • |||putative microtubule-associated protein [pompepnew.fasta]
  • SPAPB1A10.09 protein [4896.FASTAC]
  • |||microtubule-associated protein (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • low similarity to S. cerevisiae ase1, microtubule-associated protein required for anaphase spindle elongation; and human prc1, protein regulating cytokinesis [Schizosaccharomyces pombe]gi|12188973|emb|CAC21482.1| SPAPB1A10.09 [Schizosaccharomyces pombe] [nrdb_11152004_Chlamydomonas]
  • |ase1||microtubule-associated protein |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (Q9HDY1) Low similarity to S. cerevisiae ase1, microtubule-associated protein required for anaphase spindle elongation, and human prc1, protein regulating cytokinesis [pompep4896_normal_reversed]
  • |ase1||microtubule-associated protein Ase1 |Schizosaccharomyces pombe|chr 1|||Manual [pombe030305.revfasta]
  • |ase1||antiparallel microtubule cross-linking factor Ase1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAPB1A10.09 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAPB1A10.09 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Anaphase spindle elongation protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ase1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 731 amino acids

    Gene Ontology:
    Cellular Component: spindle microtubule [IDALink to PubMed article]
    spindle midzone [IDALink to PubMed article]
    microtubule cytoskeleton [IDALink to PubMed article]
    equatorial microtubule organizing center [IDALink to PubMed article]
    [NOT]spindle pole body [IDALink to PubMed article]
    cytoplasmic microtubule [IDALink to PubMed article]
    Biological Process: mitotic spindle elongation [IMPLink to PubMed article]
    spindle midzone assembly [IMPLink to PubMed article]
    dynein-driven meiotic oscillatory nuclear movement [IMPLink to PubMed article]
    microtubule bundle formation [IMPLink to PubMed article]
    [NOT]microtubule nucleation [IMPLink to PubMed article]
    regulation of cytokinesis [IMPLink to PubMed article]
    cytokinesis checkpoint [IMPLink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    microtubule binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTVMMDDIQ STDSIAEKDN HSNNESNFTW KAFREQVEKH FSKIERLHQV LGTDGDNSSL  60
   61 FELFTTAMNA QLHEMEQCQK KLEDDCQQRI DSIRFLVSSL KLTDDTSSLK IESPLIQCLN 120
  121 RLSMVEGQYM AQYDQKLSTI KEMYHKLESY CNRLGSPFVL PDFENSFLSD VSDAFTESLR 180
  181 GRINEAEKEI DARLEVINSF EEEILGLWSE LGVEPADVPQ YEQLLESHTN RPNDVYVTQE 240
  241 LIDQLCKQKE VFSAEKEKRS DHLKSIQSEV SNLWNKLQVS PNEQSQFGDS SNINQENISL 300
  301 WETELEKLHQ LKKEHLPIFL EDCRQQILQL WDSLFYSEEQ RKSFTPMYED IITEQVLTAH 360
  361 ENYIKQLEAE VSANKSFLSL INRYASLIEG KKELEASSND ASRLTQRGRR DPGLLLREEK 420
  421 IRKRLSRELP KVQSLLIPEI TAWEERNGRT FLFYDEPLLK ICQEATQPKS LYRSASAAAN 480
  481 RPKTATTTDS VNRTPSQRGR VAVPSTPSVR SASRAMTSPR TPLPRVKNTQ NPSRSISAEP 540
  541 PSATSTANRR HPTANRIDIN ARLNSASRSR SANMIRQGAN GSDSNMSSSP VSGNSNTPFN 600
  601 KFPNSVSRNT HFESKSPHPN YSRTPHETYS KASSKNVPLS PPKQRVVNEH ALNIMSEKLQ 660
  661 RTNLKEQTPE MDIENSSQNL PFSPMKISPI RASPVKTIPS SPSPTTNIFS APLNNITNCT 720
  721 PMEDEWGEEG F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..271] PSI-BLAST 21.522879 Heavy meromyosin subfragment
    2 View Details [272..350] PSI-BLAST 10.522879 No description for 2dfsA was found.
    3 View Details [351..731] PSI-BLAST 4.154902 Fibrinogen


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle