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Protein Overview: cft2

General Information:
Name(s) found: cft2 / SPBC1709.15c [Sanger Pombe]
Description(s) found:
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  • pir||T39643 probable cleavage and polyadenylation specificity factor - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582548|sp|O74740.1|CFT2_SCHPO RecName: Full=Cleavage factor two protein 2 [NCBI NR]
  • gi|3738153|emb|CAA21254.1| cleavage factor two Cft2/polyadenylation factor CPSF-73 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112240|ref|NP_595448.1| cleavage factor two Cft2/polyadenylation factor CPSF-73 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • cleavage factor two Cft2/polyadenylation factor CPSF-73 [Sanger Pombe]
  • Cleavage factor two protein 2 OS=Schizosaccharomyces pombe GN=cft2 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE CLEAVAGE AND POLYADENYLATION FACTOR SUBUNIT; CFII COMPONENT; SIMILAR TO S. CEREVISAE CFT2: O74740; [pompepVF.fasta]
  • PUTATIVE CLEAVAGE AND POLYADENYLATION FACTOR SUBUNIT; CF II COMPONENT; SIMILAR TO S. CEREVISAE CTF2: O74740; [pompepV13]
  • Putative cleavage and polyadenylation specificity factor subunit [pompep4896]
  • |||putative cleavage and polyadenylation factor subunit [pompepnew.fasta]
  • SPBC1709.15c protein [4896.FASTAC]
  • |cft2||CPF complex (PMID 14617822)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative cleavage and polyadenylation specificity factor subunit. [Schizosaccharomyces pombe]gi|3738153|emb|CAA21254.1| SPBC1709.15c [Schizosaccharomyces pombe]gi|7492481|pir||T39643 probable cleavage and polyadenylation specificity factor - fission yea [nrdb_11152004_Chlamydomonas]
  • |cft2||involved in polyadenylation |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O74740) Putative cleavage and polyadenylation specificity factor subunit [pompep4896_normal_reversed]
  • |cft2||cleavage factor two Cft2/polyadenylation factor CPSF-73 |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPBC1709.15c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC1709.15c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Cleavage factor two protein 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cft2 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 797 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    mRNA cleavage and polyadenylation specificity factor complex [IDALink to PubMed article]
    mRNA cleavage factor complex [ISSLink to PubMed article]
    Biological Process: mRNA polyadenylation [ISSLink to PubMed article]
    mRNA cleavage [ISSLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNYQCLETD SYCGTSHIEL DGIHIYIDPG SDDSLKHPEV PEQPDLILLS HSDLAHIGGL  60
   61 VYAYYKYDWK NAYIYATLPT INMGRMTMLD AIKSNYISDM SKADVDAVFD SIIPLRYQQP 120
  121 TLLLGKCSGL TITAYNAGHT LGGTLWSLIK ESESVLYAVD WNHSKDKHLN GAALYSNGHI 180
  181 LEALNRPNTL ITDANNSLVS IPSRKKRDEA FIESVMSSLL KGGTVLLPVD AASRVLELCC 240
  241 ILDNHWSASQ PPLPFPILFL SPTSTKTIDY AKSMIEWMGD NIVRDFGINE NLLEFRNINT 300
  301 ITDFSQISHI GPGPKVILAT ALTLECGFSQ RILLDLMSEN SNDLILFTQR SRCPQNSLAN 360
  361 QFIRYWERAS KKKRDIPHPV GLYAEQAVKI KTKEPLEGEE LRSYQELEFS KRNKDAEDTA 420
  421 LEFRNRTILD EDLSSSSSSE DDDLDLNTEV PHVALGSSAF LMGKSFDLNL RDPAVQALHT 480
  481 KYKMFPYIEK RRRIDEYGEI IKHQDFSMIN EPANTLELEN DSDDNALSNS NGKRKWSEIN 540
  541 DGLQQKKEEE DEDEVPSKII TDEKTIRVSC QVQFIDIEGL HDGRSLKTII PQVNPRRLVL 600
  601 IHASTEEKED MKKTCASLSA FTKDVYIPNY GEIINVSIDV NAFSLKLADD LIKNLIWTKV 660
  661 GNCEVSHMLA KVEISKPSEE EDKKEEVEKK DGDKERNEEK KEEKETLPVL NALTLRSDLA 720
  721 RAPRAAPLLV GNIRLAYLRK ALLDQGISAE LKGEGVLLCG GAVAVRKLSG GKISVEGSLS 780
  781 NRFFEIRKLV YDALAVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ste13 No Comments Unpublished Data

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..716] PSI-BLAST 54.0 No description for 2i7xA was found.
    2 View Details [717..797] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  1.48455378212673 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.980281910076056 bayes_pls_golite062009
  • catalytic activity
    		•  0.941400907161877 bayes_pls_golite062009
  • binding
    		•  0.862029507899862 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle