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Protein Overview: jmj4

General Information:
Name(s) found: jmj4 / SPCC622.19 [Sanger Pombe]
Description(s) found:
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  • pir||T41500 hypothetical protein SPCC622.19 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74627039|sp|O94606.1|JMJ4_SCHPO RecName: Full=JmjC domain-containing protein 4; AltName: Full=Jumonji domain-containing protein 4; AltName: Full=Meiotically up-regulated gene 149 protein [NCBI NR]
  • gi|4539271|emb|CAA21875.2| Jmj4 protein [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075691|ref|NP_588191.1| Jmj4 protein [Schizosaccharomyces pombe] [NCBI NR]
  • Jmj4 protein [Sanger Pombe]
  • JmjC domain-containing protein 4 OS=Schizosaccharomyces pombe GN=jmj4 PE=1 SV=1 [Swiss-Prot]
  • HYPOTHETICAL PROTEIN; CONSERVED IN FUNGI- GAILLARDIN ET AL: O94606; [pompepVF.fasta]
  • HYPOTHETICAL PROTEIN; (CONSERVED IN FUNGI- GAILLARDIN ET AL): O94606; [pompepV13]
  • Hypothetical protein [pompep4896]
  • |||hypothetical protein [pompepnew.fasta]
  • JmjC domain; transcription factor (Predicted); involved in transcriptional regulation (Predicted); involved in chromatin remodeling (Predicted); localization chromatin; no apparent orthologs (Cannot be distinguished) [4896.FASTAC]
  • |jmj4||jmjC domain|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|7491946|pir||T41500 hypothetical protein SPCC622.19 - fission yeast (Schizosaccharomyces pombe)gi|4539271|emb|CAA21875.2| jmjC domain; transcription factor (predicted); involved in transcriptional regu [nrdb_11152004_Chlamydomonas]
  • (O94606) Hypothetical protein [pompep4896_normal_reversed]
  • |jmj4|mug149|Jmj4 protein|Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPCC622.19 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPCC622.19 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |jmj4|mug149|Jmj4 protein |Schizosaccharomyces pombe|chr 3|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • JmjC domain-containing protein 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=jmj4 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 473 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [ISSLink to PubMed article]
    Biological Process: chromatin remodeling [ISSLink to PubMed article]
    regulation of transcription [ISSLink to PubMed article]
    histone demethylation [ISSLink to PubMed article]
    Molecular Function: histone demethylase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELSTYKGY SPKHGDKVPV LQNLNDLTPK DFYDKFIATR TPVIIKSSLP ESDWKGYLWQ  60
   61 QQDYLLSKIG DIVCKVEPID PVSGTFGQGM SRNEMSIKEF FQKLKNGERL YLTTQYDESN 120
  121 EVLDGDDEVS LLVKSLCPHP TDGLLTDFSI TPALMGNLVP QQCNLWIGKS ENGTSSGLHH 180
  181 DFHDNIYAVI SGYKRFVIIS PDHANQLKLS GKISKIHPNG LISYEGEDCP QRSDGLTELD 240
  241 AAIAKTQFLE KKIGSLKELA VPQESIELLE AEYENEMDRV LQMQIGGPEE DWNDLEEGDA 300
  301 ASLLDGSVGG DPESDILLNE GNDIEATSLQ DTKPELPDHF TKVSVNGLHK FMGFDDAKNV 360
  361 DVDKDELSAL AGTVPLVVDL EPGDMLYLPA SWFHEVTSSS ASSGGSDVHI AFNYWFHPPD 420
  421 NLEDFDHPYL DRNIWQAKRH LVGEAIDQLY ATNKKNEKRP AEDDSPSQKK TCQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..286] PSI-BLAST 46.0 Hypoxia-inducible factor HIF ihhibitor (FIH1)
    2 View Details [287..473] FFAS03 5.02 Hypoxia-inducible factor HIF ihhibitor (FIH1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • demethylase activity
    		•  3.52239441642457 bayes_pls_golite062009
  • DNA binding
    		•  2.56912448296176 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.2622484386078 bayes_pls_golite062009
  • binding
    		•  1.98106807488954 bayes_pls_golite062009
  • damaged DNA binding
    		•  1.1610242625285 bayes_pls_golite062009
  • catalytic activity
    		•  0.921320409505 bayes_pls_golite062009
  • protein binding
    		•  0.300532513511442 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
    		•  0.197876250194678 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle