Protein Overview: mdj1

General Information:
Name(s) found:	mdj1 / SPCC4G3.14 [Sanger Pombe]
Description(s) found: Found 20 descriptions. SHOW ALL	DNAJ domain protein Mdj1 [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	528 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA] mitochondrial inner membrane [ISS]
Biological Process:	proteolysis [ISS] protein folding [ISS]
Molecular Function:	zinc ion binding [IEA] unfolded protein binding [ISS] Hsp70 protein binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSKYLQSRV CGLHSFTNSS AQQLFSKSIA HSSRRNFVIS SSCTKFRNVA IQRNAKREFS  60
   61 RCAALKNFSY HARCFHATRA VWEMTDPYKT LGVSKSASAS EIKSAYYKLA KQYHPDANPD 120
  121 KAAQDKFVEI KQAYEVLQDP KKKKAFDTYG AGAFKNGEFT GGDFEGFQNG FAGASSFSSG 180
  181 FPGFNFEDLF GFSSRGPQAR RNTSFDVFVG EDIEASITID FMEAVRGAKK DLSYSVSSTC 240
  241 SSCHGSGLQP GSHKSTCFAC KGTGQRLHFI PPSFHMQTTC DSCGGTGTTI PPNSACRSCM 300
  301 GSGTVRERKT VSIDIPPGID DNTVLRVMGA GNDASTAKGG PNAKSRPGDL FATIHVRKHP 360
  361 FFVREGTNVT YNAKIPMTTA ALGGTLRVPT LTGNVDLRVS PGTSTGDRIT MAGKGIRKVN 420
  421 TSRYGNFYVN FEVTIPKILS PHERSLLEQL ADALNDSTAR RTQSSPSGTN SSTSTSSTSS 480
  481 KHSTGISTEP TTGEENKQDG SVGGFFKRAF RRLHPDEDQN PKKDESSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..83]	deduced	N/A	No confident structure predictions are available.
2	View Details	[84..201]	PSI-BLAST	23.0	J-DOMAIN (RESIDUES 1-77) OF THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 1-104) OF THE MOLECULAR CHAPERONE DNAJ, NMR, 20 STRUCTURES
3	View Details	[202..528]	PSI-BLAST	50.39794	The crystal structure of Hsp40 Ydj1

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
unfolded protein binding	3.04403163860617	bayes_pls_golite062009
protein binding	2.65982681685488	bayes_pls_golite062009
binding	2.63138872417193	bayes_pls_golite062009
transcription regulator activity	2.31739509739943	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
DNA binding	1.88444505115207	bayes_pls_golite062009
nucleic acid binding	1.73387701301727	bayes_pls_golite062009
chaperone binding	1.61155546076854	bayes_pls_golite062009
transporter activity	1.29863098651348	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	0.927337691912581	bayes_pls_golite062009
enzyme regulator activity	0.675735261884317	bayes_pls_golite062009
protein transporter activity	0.599800483479766	bayes_pls_golite062009
substrate-specific transporter activity	0.557328784636827	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
GTPase regulator activity	0.130185025729857	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009

3

Term	Confidence	Notes
binding	2.7298921704023	bayes_pls_golite062009
protein binding	2.6297172985864	bayes_pls_golite062009
protein disulfide isomerase activity	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	2.23398279564144	bayes_pls_golite062009
unfolded protein binding	2.04158808514315	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	0.594882036388263	bayes_pls_golite062009
receptor binding	0.395342079633271	bayes_pls_golite062009
enzyme regulator activity	0.301226589648736	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle