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Protein Overview: SPAC4F10.04

General Information:
Name(s) found: SPAC4F10.04 [Sanger Pombe]
Description(s) found:
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  • pir||T38808 probable phosphotyrosyl phosphatase activator - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582062|sp|O36016.1|PTPA1_SCHPO RecName: Full=Serine/threonine-protein phosphatase 2A activator 1; AltName: Full=Peptidyl-prolyl cis-trans isomerase PTPA-1; Short=PPIase PTPA-1; Short=Rotamase PTPA-1; AltName: Full=Phosphotyrosyl phosphatase activator [NCBI NR]
  • gi|2388975|emb|CAB11707.1| protein phosphatase type 2A, intrinsic regulator (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19115659|ref|NP_594747.1| protein phosphatase type 2A, intrinsic regulator (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • protein phosphatase type 2A, intrinsic regulator [Sanger Pombe]
  • Serine/threonine-protein phosphatase 2A activator 1 OS=Schizosaccharomyces pombe GN=rrd1 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE PHOSPHOTYROSYL PHOSPHATASE ACTIVATOR: O36016; [pompepVF.fasta]
  • Putative phosphotyrosyl phosphatase activator [pompep4896]
  • |||putative phosphotyrosyl phosphatase activator [pompepnew.fasta]
  • SPAC4F10.04 protein [4896.FASTAC]
  • |||protein phosphatase type 2A, intrinsic regulator activity (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative phosphotyrosyl phosphatase activator [Schizosaccharomyces pombe]gi|2388975|emb|CAB11707.1| SPAC4F10.04 [Schizosaccharomyces pombe]gi|7492830|pir||T38808 probable phosphotyrosyl phosphatase activator - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||protein phosphatase type 2A, intrinsic regulator activity |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O36016) Putative phosphotyrosyl phosphatase activator [pompep4896_normal_reversed]
  • |||protein phosphatase type 2A, intrinsic regulator |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC4F10.04 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Serine/threonine-protein phosphatase 2A activator 1 (Peptidyl-prolyl cis-trans isomerase PTPA-1) (PPIase PTPA-1) (Rotamase PTPA-1) (Phosphotyrosyl phosphatase activator 1) [nr-271106-contam.fasta]
  • hypothetical protein SPAC4F10.04 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |rrd1||protein phosphatase type 2A, intrinsic regulator Rrd1 |Schizosaccharomyces pombe|chr 1|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Serine/threonine-protein phosphatase 2A activator 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rrd1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 325 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: signal transduction [RCALink to PubMed article]
    regulation of DNA repair [ISSLink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    regulation of mitotic spindle organization [ISSLink to PubMed article]
    Molecular Function: peptidyl-prolyl cis-trans isomerase activity [IEA]
    phosphatase activator activity [IEA]
    protein phosphatase type 2A regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVVDEKTIL ELENERFDES SQFKTPEKLI VEASDMTAFR QSKAYYRIFD FLQRLNIASV  60
   61 GVNDYHVEYS TRVEKLVRIL CRVKEITKTV PPASGRHRFG NPAFRIWHEK LRDSASQIMD 120
  121 IIIPDSLSKA KVELLDYFLG SFGNSQRIDF GTGHELNFLG FIKGLDLLGL LDAADYKAIA 180
  181 LYITHVYLEV CRELVQTYRL EPAGSHGVWG LDDHFFIPYI FGSAQLADKA SSSIIKPDAI 240
  241 LNKKIVDEKA NSNLYFSAIK FINVMKKGPF YEHSPILYDI TAVPIWSKVN QGLIKMYDVE 300
  301 VLSKYPVVQH FHFGNLFPFN PLVAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..325] PSI-BLAST 147.0 No description for 2hv6A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein phosphatase 2A binding
    		•  8.91440374532471 bayes_pls_golite062009
  • protein phosphatase type 2A regulator activity
    		•  8.6639960888548 bayes_pls_golite062009
  • phosphatase activator activity
    		•  8.3056988507343 bayes_pls_golite062009
  • protein tyrosine phosphatase activator activity
    		•  8.25208483660706 bayes_pls_golite062009
  • phosphatase regulator activity
    		•  6.19500533578098 bayes_pls_golite062009
  • protein phosphatase regulator activity
    		•  6.15684302555811 bayes_pls_golite062009
  • hydrolase activity
    		•  2.45059495047304 bayes_pls_golite062009
  • protein phosphatase binding
    		•  2.00937322119814 bayes_pls_golite062009
  • phosphatase binding
    		•  1.91058768875586 bayes_pls_golite062009
  • binding
    		•  1.8791829282582 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.7601888817048 bayes_pls_golite062009
  • protein binding
    		•  1.54296590753075 bayes_pls_golite062009
  • enzyme binding
    		•  0.93814259527019 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.877491580866805 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.382201469725949 bayes_pls_golite062009
  • catalytic activity
    		•  0.262417313750414 bayes_pls_golite062009
  • receptor binding
    		•  0.23629695620438 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.0723700055105033 bayes_pls_golite062009
  • ATP binding
    		•  0.00395016899365508 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle