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Protein Overview: SPAC26A3.10

General Information:
Name(s) found: SPAC26A3.10 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • Arf GAP protein [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 923 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    cell tip [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: small GTPase mediated signal transduction [NAS]
    regulation of GTPase activity [ISSLink to PubMed article]
    regulation of ARF GTPase activity [IEA]
    intracellular protein transport [RCALink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    ARF GTPase activator activity [IEA]
    GTPase activator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGSDSLLKS VDVSKLDNGS TISFRAREDG FLESISSSSG KLVDMVLDST SKECLPKFSF  60
   61 QNKLDFYFLF SDRVLQLQKE RKVLVLIHCE SLQSFDSFFA QKLKYADLIS SDNVHEIFLP 120
  121 DSNAANIRYH WEWSPPSGKL LEYECKNYSC IAVYSTEDCT LERISKFSYY TVSRCGDSMD 180
  181 DTFFSESQRV TSPLTTSQTV QTQPPQSPEA KTELSLINTK TVIFPENYED GPSFRSMLHE 240
  241 LEQKSSLMKY YCKKIMKRIV QLSDAYDASQ VAVMKLSETL SEASNSTSMN MDILLDSYLT 300
  301 KAMDIHATFI QKLNYDLINL LYEPFHNIYS SFIKPIDDRR LEFDEQSKSF YGSLSRYLSA 360
  361 KKDKKGGDSK FFQKEKTFAL QRYDYYCFMQ DLHDGSIIND INGIFLQYFH RQYDHIALFS 420
  421 NLMNSVLPNL QQLNLKLEKT KWSTTRRDKG REMHRSQVIQ TSGRPKSMAP PSPSPISPSF 480
  481 PLHEIQSPMP NRRMAASADD ISQTSNFTTE IKGKCISNGG SASPDKIFKE GLLLVFGATE 540
  541 LGTDLAMVSK AAWHKHWIVV ENGSLWEYAN WKDSVKSNVS SISLKHASAD KVRKQGRRFC 600
  601 FEVVTPKLKR LYQATSAEEM DSWIEAICEA AKISSFQLSR VATPLSASVR RPSKVFPLFS 660
  661 TSFETTPISR KLSGSGIKKA FSRKGSWNLQ QFFRSDNSGT MHMEQLERYH ASANIFIQML 720
  721 RKTDVSNSVC ADCGSVKDVT WCSINIPVVL CIECSGIHRS LGTHISKTRS LLLDSLSQQS 780
  781 KVLLCKIGNA AVNRVYEKGL SNPSLKPKPE HNAQVKLAFA QKKYVEHAFI DFAGVDADAT 840
  841 LLEGLEQNKI SKILLGLAAK PNFEENGVVF LKAVTRDTSK LHLLELLFMN GLLLPDSEQL 900
  901 SEHVSPDMQS YLSQKQFTKY LKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..196] MSA 2.065952 View MSA. No confident structure predictions are available.
    2 View Details [197..700] PSI-BLAST 30.0 No description for 2elbA was found.
    3 View Details [701..923] PSI-BLAST 44.69897 Crystal structure of UPLC1 GAP domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.65091781683225 bayes_pls_golite062009
  • protein binding
    		•  2.12168271674167 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.66986263418539 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.64990514605397 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.55319485371003 bayes_pls_golite062009
  • signal transducer activity
    		•  1.55319485371003 bayes_pls_golite062009
  • transporter activity
    		•  1.28986800087234 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.2550809703725 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.25381967078645 bayes_pls_golite062009
  • enzyme binding
    		•  1.17212675145623 bayes_pls_golite062009
  • phospholipid binding
    		•  1.09683218092034 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.90578029954417 bayes_pls_golite062009
  • small GTPase binding
    		•  0.8507658747425 bayes_pls_golite062009
  • GTPase binding
    		•  0.82889812790119 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.745321902095093 bayes_pls_golite062009
  • phosphoinositide binding
    		•  0.71817045430443 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.54401901869178 bayes_pls_golite062009
  • receptor binding
    		•  0.50127063593663 bayes_pls_golite062009
  • kinase binding
    		•  0.39940885913863 bayes_pls_golite062009
  • receptor activity
    		•  0.353510125274044 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.207829786337892 bayes_pls_golite062009
  • lipid binding
    		•  0.179561240451969 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase signaling protein activity
    		•  0.13700176999256 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.10105990547756 bayes_pls_golite062009
  • protein kinase binding
    		•  0.0918356351234999 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle