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Protein Overview: spt6

General Information:
Name(s) found: spt6 / SPAC1F7.01c [Sanger Pombe]
Description(s) found:
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  • gi|63054631|ref|NP_594487.2| transcription elongation factor Spt6 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|19862908|sp|Q09915.2|SPT6_SCHPO RecName: Full=Transcription elongation factor spt6; AltName: Full=Chromatin elongation factor spt6 [NCBI NR]
  • gi|159884008|emb|CAB71845.2| transcription elongation factor Spt6 [Schizosaccharomyces pombe] [NCBI NR]
  • transcription elongation factor Spt6 [Sanger Pombe]
  • (Q09915) Hypothetical protein C1F7.01c in chromosome I [Swiss-Prot]
  • Transcription elongation factor spt6 OS=Schizosaccharomyces pombe GN=spt6 PE=1 SV=2 [Swiss-Prot]
  • POSSIBLY INVOLVED IN CHROMATIN ARCHITECTURE; SIMILAR TO S. CEREVISIAE SPT6: Q09915;Q9P7T3; [pompepVF.fasta]
  • PUTATIVE INVOLVEMENT IN CHROMATIN STRUCTURE; YEAST SPT6-LIKE: Q09915;Q9P7T3; [pompepV13]
  • Hypothetical protein C1F7.01c in chromosome I [pompep4896]
  • ||SPAC694.07c|possibly involved in chromatin architecture [pompepnew.fasta]
  • ||SPAC694.07c|involved in chromatin remodeling (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • |spt6|SPAC694.07c|involved in chromatin remodeling |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • |spt6|SPAC694.07c|transcription elongation factor Spt6|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Transcription elongation factor spt6 (Chromatin elongation factor spt6) [nr-271106-contam.fasta]
  • hypothetical protein SPAC694.07c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |spt6|SPAC694.07c|transcription elongation factor Spt6 |Schizosaccharomyces pombe|chr 1|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Transcription elongation factor spt6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spt6 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 1365 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [ISSLink to PubMed article]
    transcription elongation factor complex [ISS]
    mitochondrion [ISS]
    Biological Process: histone exchange [NASLink to PubMed article]
    regulation of RNA elongation [IC]
    regulation of transcription by chromatin organization [ISS]
    DNA replication-independent nucleosome assembly [ISSLink to PubMed article]
    RNA elongation from RNA polymerase II promoter [ISSLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [IEA]
    Molecular Function: hydrolase activity, acting on ester bonds [IEA]
    RNA polymerase II transcription elongation factor activity [ISS]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSENEVVGSP TTNGDKNEDG YPAENGEGTN VDDNNNEEEK DGIPLDNDND ENDSSEESAT  60
   61 DEEAERQVRE GFIVEDEEDE VPQEIRRKKK RKKHAESTAD QDMLDEEDLE LVMENTGQGS 120
  121 RFSKLRRLKR GRDQEETLEN IFSEEEEEEE NEVDDEAPNR TQGHRAGVID EFADFIEQDE 180
  181 FEDEERQEEK YETGPPIESV RPEALGISDD DYIQIYEVFG DGTDYAFALE DEDAEDELEE 240
  241 SVSLKTIFEP SELKDKMLTE EDEIIRITDE PERMQLYMKR NIDCSEDEFR EQVAWIIDYL 300
  301 LKNRRDIDAE LYEPFQTAVR YVVHFFIRDS LEVPFIWQHR RDYIVHNNRE RNTITPLLSQ 360
  361 NDLWNIFFLC TKFWSLHSKK QDILKLYSDL GINDDLVVPF CEAASSLDAI DDLNDYIHFT 420
  421 YSEQIRDRAL LMGTGLRRPQ GSKYSFFEKF RKSSLYNLVK EFGMSAKDFS FNVAQGARLR 480
  481 FVEDNTLSPE ELSRTYVTNE LSSPEQVLQK ARRVLAEEII HDPQFRKSFR DKLYNAGVVT 540
  541 VLATQKGVRK IGSEHPYYEF KYLKRKPLGS FELEPILFLK MLKAEEEGLI QLSIEFEDPD 600
  601 DVFKGLLELF VSDNFSENAM QWNAQRELVL KEVFKRFSAL APDAIRETLR SRYLDELGMR 660
  661 CRNQLFSRLD QAPYEPSTKN FDRGTIPSVL AVSNGKGESS DAIICVFVDD VGEPTDSLKL 720
  721 ADLRDLANQA MFAEFVEKVK PDVIGVSGMS VSAHKIRQHV QDSLTSHEPV DLIMVNDEVA 780
  781 RLYQNSTRAV DEFPTLPTIS CYCVALARYV QNPLFEYAAM GRDLMSLSFD PWQHLLPPDV 840
  841 LWKYLETALV DISSLVGIDI NEAVTNKYEA NILPYIAGLG PRKADYVLKK IAATGGRIDN 900
  901 RSDLISKQIM SRKVFINCSS FFIIPNDEYP NMDILDSTRI HNEDYELARK MASDALELDE 960
  961 EDIEELETNR GVVYHLLEEN ETGKLDELVL EEYADQLERE FHQKKRNTLE KIRLELKDPY1020
 1021 GEQRNVFHKL TPSEIFLMLT GENPEELQAD AIVPVNVRRV TNRFVAVKLD CGIDGNIKAD1080
 1081 EVSDDFIPPP QLLQVGQTVE GVIISLDEAN FMVDLSLRNS VLQSANSKRQ TSSHRTSYWD1140
 1141 TEAEKRDTER MQAETQAEQR VARVIKHPLF KDLNASQAEA YLSKMQVGDL VIRPSSKGSD1200
 1201 HIVVTWKVAE GSYQHIDVLE LEKENEFTIG QKLLVKGRFE KMTYQYSDLD ELIVLHIKAI1260
 1261 AKKIDEMCIH DKFRKGTQAE TEKWLESYSE ANPKRSCYAF CFDHQHPGYF ILCFKASVNS1320
 1321 PVTAWPVKVI PNAFFLQGNV YGDMTALCNG FKLLYAARTK NFRRM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle