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Protein Overview: gef2

General Information:
Name(s) found: gef2 / SPAC31A2.16 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • RhoGEF Gef2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1101 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of Rho protein signal transduction [IEA]
    regulation of catalytic activity [ICLink to PubMed article]
    Molecular Function: Rho guanyl-nucleotide exchange factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVGTMGSRA ELLAISIQFG GLWVFRDLLQ MNPLFEQDHV FCTFNHPNMG LVLISFAKVD  60
   61 GHILAAYALS KLGPDTFSIC YPFSSKLDAF AQTLDLEWQI ASMHKEAAAC VYEFLCVESV 120
  121 CLHTGENWRE SVIEPEYASY IFDTINVFQS SSLTRELYSL GEPNGVREFV VDAIFDIKVD 180
  181 NSWWEDPSNS YWKTVIGSRE MFEDSRKKTS SPSPSFASSK DAGTIPAIQK KKSLLIEMME 240
  241 TESTYVERLR HLVNDYALPL RDLAKSSKKL LGLYELNTLF PPCLNKLIQL NSAFLDEFEA 300
  301 IMSDLNFEDI DEKKFEEIDL RLACCFESHF FAFSQHYPRY LEQSNDFGNV LKMASKIPKF 360
  361 VEFHDQVKLN ANMNVGLSQL IMEPVQRIPR YSLFLDQIIL LTQEGECQHT YVRSVEIIKN 420
  421 IAEMPTVDAE ERSRIFAGLQ HIIPDLAPNM ISNSRNFIDC IDVTREFLKN GQLHLIPYTL 480
  481 ILFNDRICLV QRRSKSSIAS TILDLRKQNP RNSYSKEKRA QYIGSNMNEA VELTRSMVEE 540
  541 NTIFLISKYA SSPSFFNEYP ILKFRCDFEN VRTMDRFYQS FQKALSMNKS QPSCLSFSKL 600
  601 NDFVVFFNNY SRFEYEKESK RSDIVCICTN DANVDKHKFL QDGNIVITFF QQDEDFHLSF 660
  661 DSWLGVSLPT EAVIAKEDLR EACLNYLINI KRLLLCPFSN RNFSSLDLYS NLIQHLLSAN 720
  721 SSPRKSRLSF GGRPGSPSKI SLSLNRFYNQ GGLSKSCATL PSQMYNLDHN NISQKSLKFN 780
  781 THNTSKASAE KTVEHLEAFK GGFKYHTDLK NLLYPLSEKE KIEGDELYDN ILKETFNEEL 840
  841 LSHYPPNIIY ATFQKYLSSF INRKFGVLLS SSFIQQLNTV ENLNLSFNST DAVYHLKKIL 900
  901 QDLPESSLKI LENIFSIASD LLLRLPLKDQ CDFVTKQLAI ALAPSMFGSN AVELVYYLAY 960
  961 HSDRIFGTVE ELPTPVSPAN SNNDKQLDES KFQAIAMKEM PERHPKEILP GQIEREAYED1020
 1021 LRRKYHLTLA RLAQMTRLNE DSKKSIPLLY DRFNHDLKLI KQSVQASLIR KQCELDTAKW1080
 1081 TLEEYESKLN AKEGCQTNIF I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] deduced N/A No confident structure predictions are available.
    2 View Details [86..611] PSI-BLAST 63.0 No description for 2pz1A was found.
    3 View Details [612..685] PSI-BLAST 5.0 Solution structure of rat Kalirin N-terminal SH3 domain
    4 View Details [686..844] MSA 1.038968 View MSA. No confident structure predictions are available.
    5 View Details [845..978] deduced N/A Confident ab initio structure predictions are available.
    6 View Details [979..1101] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle