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Protein Overview: alp31

General Information:
Name(s) found: alp31 / SPAC8E11.07c [Sanger Pombe]
Description(s) found:
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  • gi|6831694|sp|Q9Y703.1|TBCA_SCHPO RecName: Full=Tubulin-specific chaperone A; AltName: Full=Tubulin-folding cofactor A; Short=CFA; AltName: Full=Altered polarity protein 31 [NCBI NR]
  • gi|5381218|dbj|BAA82293.1| Alp31 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|4582224|emb|CAB40194.1| tubulin specific chaperone cofactor A, Alp31 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19115074|ref|NP_594162.1| tubulin specific chaperone cofactor A [Schizosaccharomyces pombe] [NCBI NR]
  • pir||T43514 beta-tubulin folding cofactor A homolog - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • tubulin specific chaperone cofactor A [Sanger Pombe]
  • Tubulin-specific chaperone A OS=Schizosaccharomyces pombe GN=alp31 PE=2 SV=1 [Swiss-Prot]
  • TUBULIN SPECIFIC CHAPERONE A: Q9Y703; [pompepVF.fasta]
  • Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (Altered polarity protein 31) [pompep4896]
  • |alp31||tubulin specific chaperone A (PMID 10978278) [pompepnew.fasta]
  • |alp31||chaperone activity|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative chaperonin cofactor a [Schizosaccharomyces pombe]gi|4582224|emb|CAB40194.1| SPAC8E11.07c [Schizosaccharomyces pombe]gi|6831694|sp|Q9Y703|TBCA_SCHPO Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (Altered polarity protein 31)gi [nrdb_11152004_Chlamydomonas]
  • (Q9Y703) Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (Altered polarity protein 31) [pompep4896_normal_reversed]
  • |alp31||tubulin specific chaperone |Schizosaccharomyces pombe|chr 1|||Manual [pombe030305.revfasta]
  • |alp31||tubulin specific chaperone cofactor A, Alp31|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Alp31 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC8E11.07c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC8E11.07c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Tubulin-specific chaperone A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=alp31 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 119 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: post-chaperonin tubulin folding pathway [IMPLink to PubMed article]
    protein folding [IGILink to PubMed article]
    establishment or maintenance of microtubule cytoskeleton polarity [IMPLink to PubMed article]
    Molecular Function: beta-tubulin binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNTVRSLVI KTNVVKRIIK DVELAHIDIN EAEKRVQSKI DNGEDSAEIE HQKFVLKKHL  60
   61 EALPDALVRL RNATNDLESI SSDSAYEGTP ELEQANEYLE KAKEVIEKEQ TNFPTNGYH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] PSI-BLAST 19.522879 Tubulin chaperone cofactor A

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.09728509318083 bayes_pls_golite062009
  • tubulin binding
    		•  1.81432377631684 bayes_pls_golite062009
  • chaperone binding
    		•  1.51621791371755 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.23677613770082 bayes_pls_golite062009
  • protein binding
    		•  1.10534436186662 bayes_pls_golite062009
  • beta-tubulin binding
    		•  0.335453515773179 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle