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Protein Overview: SPCC1620.08

General Information:
Name(s) found: SPCC1620.08 [Sanger Pombe]
Description(s) found:
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  • pir||T41038 atp-specific succinyl-coa synthetase beta subunit - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|4008575|emb|CAA22492.1| succinate-CoA ligase (beta subunit) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|21264033|sp|O94415.1|SUCB_SCHPO RecName: Full=Probable succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial; AltName: Full=Succinyl-CoA synthetase beta chain; Short=SCS-beta; Flags: Precursor [NCBI NR]
  • gi|19075966|ref|NP_588466.1| succinate-CoA ligase (beta subunit) [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • succinate-CoA ligase [Sanger Pombe]
  • Probable succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Schizosaccharomyces pombe GN=SPCC1620.08 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE ATP-SPECIFIC SUCCINYL-COA SYNTHETASE BETA SUBUNIT: O94415; [pompepVF.fasta]
  • ATP-SPECIFIC SUCCINYL-COA SYNTHETASE BETA SUBUNI T: O94415; [pompepV13]
  • Probable succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial precursor (EC 6.2.1.4) (Succinyl-CoA synthetase, beta chain) (SCS-beta) [pompep4896]
  • |||putative ATP-specific succinyl-CoA synthetase beta subunit [pompepnew.fasta]
  • |||succinate-CoA ligase (beta subunit) (predicted)|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • atp-specific succinyl-coa synthetase beta subuni t [Schizosaccharomyces pombe]gi|4008575|emb|CAA22492.1| SPCC1620.08 [Schizosaccharomyces pombe]gi|7490140|pir||T41038 atp-specific succinyl-coa synthetase beta subunit - fission yeast (Schizosaccharomyces [nrdb_11152004_Chlamydomonas]
  • |||succinate-CoA ligase |Schizosaccharomyces pombe|chr 3|||Manual [pompep2242005.fasta]
  • (O94415) Probable succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial precursor (EC 6.2.1.4) (Succinyl-CoA synthetase, beta chain) (SCS-beta) [pompep4896_normal_reversed]
  • SPCC1620.08 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPCC1620.08 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Probable succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial precursor (Succinyl-CoA synthetase, beta chain) (SCS-beta) [nr-271106-contam.fasta]
  • |||succinate-CoA ligase beta subunit |Schizosaccharomyces pombe|chr 3|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Probable succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC1620.08 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 433 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article][ISSLink to PubMed article]
    succinate-CoA ligase complex [ICLink to PubMed article]
    Biological Process: tricarboxylic acid cycle [ISSLink to PubMed article]
    succinyl-CoA metabolic process [ISSLink to PubMed article]
    Molecular Function: GTP binding [IEA]
    succinate-CoA ligase (GDP-forming) activity [IEA]
    ATP binding [IEA]
    succinate-CoA ligase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTRSVLRKA PRAFSPFLQK RNLALHEYIS HDILRKFGVD VPRGAPARSG EEAEKVARDL  60
   61 KVTDLVVKAQ VLAGGRGKGQ FDSGLRGGVR PVYDATEARM FAEQMIGHKL ITRQTGPAGK 120
  121 ICNVVYVCER KFIRKEYYFA ILMDRENQCP MIVASDQGGV DIETVAAENP SAIIKRSLPN 180
  181 SPNLDPHIAE ELVDKLGFSS SSKPKAVDAI VKLYKVFNDC DATQVEINPL AETTDHKVLC 240
  241 MDAKLNFDDN AEFRHSNIFV LRDISQEDPD EARAAKVGLN FIKLDGNIGC LVNGAGLAMA 300
  301 TMDIIKLHGG EPANFLDVGG NANAEAIREA FSLITNDPKT TAIFVNIFGG IVRCDVIAKG 360
  361 LISVVSALNL NIPIICRLQG TNQGAAKEVI NNSGLRIFSF DDLDEAAKKA CRFSRVVEMA 420
  421 READVNVSFE LPL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..433] PSI-BLAST 88.69897 Crystal structure of pig GTP-specific succinyl-CoA synthetase in complex with GTP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • succinate-CoA ligase (GDP-forming) activity
    		•  9.38156037766008 bayes_pls_golite062009
  • succinate-CoA ligase activity
    		•  9.37213380498009 bayes_pls_golite062009
  • CoA-ligase activity
    		•  8.19630272128785 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  7.98453115335343 bayes_pls_golite062009
  • succinate-CoA ligase (ADP-forming) activity
    		•  7.27105019329796 bayes_pls_golite062009
  • ligase activity, forming carbon-sulfur bonds
    		•  7.23103788464777 bayes_pls_golite062009
  • ligase activity
    		•  3.25077459445999 bayes_pls_golite062009
  • ATP citrate synthase activity
    		•  3.09252003125984 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  3.07329302783164 bayes_pls_golite062009
  • catalytic activity
    		•  2.5009559386228 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  1.75094739650292 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  1.59015373957506 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  1.29064883699349 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.15639517822408 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.992008268375695 bayes_pls_golite062009
  • binding
    		•  0.346654244533873 bayes_pls_golite062009
  • biotin carboxylase activity
    		•  0.0172732430077291 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle