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Protein Overview: sec61

General Information:
Name(s) found: sec61 / SPBC354.02c [Sanger Pombe]
Description(s) found:
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  • pir||T40282 endoplasmic reticulum translocase sec61 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|2950452|emb|CAA17802.1| translocon alpha subunit Sec61 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|2500734|sp|P79088.1|SC61A_SCHPO RecName: Full=Protein transport protein sec61 subunit alpha [NCBI NR]
  • gi|19112018|ref|NP_595226.1| translocon alpha subunit Sec61 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|1870152|emb|CAA72200.1| SEC61 protein [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1870150|emb|CAA72199.1| SEC61 protein [Schizosaccharomyces pombe] [NCBI NR]
  • translocon alpha subunit Sec61 [Sanger Pombe]
  • Protein transport protein sec61 subunit alpha OS=Schizosaccharomyces pombe GN=sec61 PE=2 SV=1 [Swiss-Prot]
  • (P79088) Protein transport protein sec61 alpha subunit [Swiss-Prot]
  • PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT; SUBCELLULAR LOCALIZATION OF GFP FUSION- MEMBRANE: P79088;Q9UU67; [pompepVF.fasta]
  • PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT; SUBCELLULAR LOCALIZATION OF GFP FUSION -MEMBRANE: P79088;Q9UU67; [pompepV13]
  • Protein transport protein sec61 alpha subunit [pompep4896]
  • |sec61||protein transport protein [pompepnew.fasta]
  • |sec61||translocon (alpha subunit) (predicted) (PMID 9427389)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • protein transport protein sec61 alpha subunit. [Schizosaccharomyces pombe]gi|1870152|emb|CAA72200.1| SEC61 protein [Schizosaccharomyces pombe]gi|1870150|emb|CAA72199.1| SEC61 protein [Schizosaccharomyces pombe]gi|2950452|emb|CAA17802.1| sec61 [Schizosa [nrdb_11152004_Chlamydomonas]
  • |sec61||translocon |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • |sec61||translocon alpha subunit Sec61|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Protein transport protein sec61 subunit alpha [nr-271106-contam.fasta]
  • SEC61 protein [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • SPBC354.02c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • translocon subunit alpha [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Protein transport protein sec61 subunit alpha OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sec61 PE=2 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 479 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    endoplasmic reticulum [IDALink to PubMed articleLink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    Sec61 translocon complex [ISSLink to PubMed article]
    Biological Process: SRP-dependent cotranslational protein targeting to membrane, translocation [ISSLink to PubMed article]
    posttranslational protein targeting to membrane [ISSLink to PubMed article]
    Molecular Function: ribosome binding [NASLink to PubMed article]
    P-P-bond-hydrolysis-driven protein transmembrane transporter activity [IEA]
    protein transporter activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDLRFLDLV KPFAPFLPEI AAPERKVPFK QKMLWTGVTL LIFLVMSQVP LYGIVSSDSS  60
   61 DPLLWLRMIL AANRGTLMEL GISPIVTSSM LVQLLVGSQL IEVNMELKSD REMYQLVQKF 120
  121 LAIIIAFGQA TAYVLTGMYG RPQDLGAGIC LLLILQLAAA SLIVLLLDEL LQKGYGLGSG 180
  181 ISLFIATINC ENIFWKAFSP TTYHIANGVQ FEGAVINFVY VMFTWDNKAA ALYQAFFRSG 240
  241 LTSSQIQLPN LWNFFATLLV FGVVIYLQDF RVEIPIRSQK FRGYRSTFPV KLLYTSNTPI 300
  301 MLQSALTSNL FFASRLLFNR FSSNFLVRFL GVWEQTATSG LSYYLSPPAS FQDALIDPIH 360
  361 TLVYVFFTMF ACALFSKLWI EVSGASPRDV AKQLKSQQLV MAGHREGSMY KELKRIIPTA 420
  421 AWLSGAVVGA LAVASDLLGA LGSGTAVLLC TTTIYGYYEQ LQKEIKGDQY GLPVTPMMQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..479] PSI-BLAST 74.522879 The structure of a protein conducting channel

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonucleoprotein binding
    		•  5.96221631042313 bayes_pls_golite062009
  • protein transporter activity
    		•  5.55929343005534 bayes_pls_golite062009
  • transporter activity
    		•  3.32223562584466 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.22714325269757 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  2.12732472524264 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  2.12732472524264 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  1.76187269823414 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.67782980643723 bayes_pls_golite062009
  • binding
    		•  1.4562802789412 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.42890247609405 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.15847548838424 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.15316743403707 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.10003802565492 bayes_pls_golite062009
  • peptide transporter activity
    		•  1.01893828721893 bayes_pls_golite062009
  • protein binding
    		•  0.674651002700028 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle