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Protein Overview: SPBC16G5.10

General Information:
Name(s) found: SPBC16G5.10 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • exosome subunit Rrp42 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 299 amino acids

    Gene Ontology:
    Cellular Component: cytoplasmic exosome (RNase complex) [ISSLink to PubMed article]
    nuclear exosome (RNase complex) [ISSLink to PubMed article]
    nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    nucleolus [IEA]
    Biological Process: rRNA processing [ISSLink to PubMed article]
    mRNA catabolic process [ISSLink to PubMed article]
    Molecular Function: 3'-5'-exoribonuclease activity [ISSLink to PubMed article]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLSLPELSY THKSITEFEP AIRNDGRSID QLRPLSGQVD VLPGTNGSAR VKWASSVEIV  60
   61 IGVKAEVGDA TPEGGKYVAS VEISPSVSIQ NRETDEIPSF LTSALQDLLN ALAVDYLKFT 120
  121 PSKAWIIHVD AVVILSSSPY ENILSALSLA AYLALQTTRL PKISTPNVTD ITIGSTKYEP 180
  181 SEEYDVDSEW ENALPLQGLE LMSVIILVSS IDQVIIVDPT IEESSVAQVT YAIGVQASGA 240
  241 ISYTRVVGTG GGYASTGRAI TVERYIELLE TASTVGTKLL NASSDILSFK GLGFFDILP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..299] PSI-BLAST 59.69897 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • exoribonuclease activity
    		•  7.55877202113513 bayes_pls_golite062009
  • ribonuclease activity
    		•  7.54644729272203 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  7.5310318714913 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  6.46930372693262 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  4.29895100594643 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  3.83939403332553 bayes_pls_golite062009
  • exonuclease activity
    		•  3.40686901061667 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.24341202600661 bayes_pls_golite062009
  • RNA binding
    		•  2.47373172667773 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.71222144385878 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.52108547421872 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.45130233071198 bayes_pls_golite062009
  • binding
    		•  1.38311294671926 bayes_pls_golite062009
  • structural molecule activity
    		•  1.19756544622048 bayes_pls_golite062009
  • transcription termination factor activity
    		•  1.01993495617192 bayes_pls_golite062009
  • DNA binding
    		•  1.01454217691792 bayes_pls_golite062009
  • hydrolase activity
    		•  0.722411371082264 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.51810239718467 bayes_pls_golite062009
  • mRNA binding
    		•  0.403794675006504 bayes_pls_golite062009
  • protein binding
    		•  0.292595239533272 bayes_pls_golite062009
  • ATP-dependent peptidase activity
    		•  0.1173709890655 bayes_pls_golite062009
  • catalytic activity
    		•  0.10089766806364 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0287026367466632 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle