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Protein Overview: rpo41

General Information:
Name(s) found: rpo41 / SPAC26H5.12 [Sanger Pombe]
Description(s) found:
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  • pir||T38431 DNA-directed RNA polymerase precursor, mitochondrial - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|3914825|sp|O13993.1|RPOM_SCHPO RecName: Full=DNA-directed RNA polymerase, mitochondrial; Flags: Precursor [NCBI NR]
  • gi|2398821|emb|CAB16197.1| mitochondrial RNA polymerase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19115371|ref|NP_594459.1| mitochondrial DNA-directed RNA polymerase [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • mitochondrial DNA-directed RNA polymerase [Sanger Pombe]
  • DNA-directed RNA polymerase, mitochondrial OS=Schizosaccharomyces pombe GN=rpo41 PE=2 SV=1 [Swiss-Prot]
  • DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL: O13993; [pompepVF.fasta]
  • DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL PRECURSOR: O13993; [pompepV13]
  • DNA-directed RNA polymerase, mitochondrial precursor (EC 2.7.7.6) [pompep4896]
  • |||DNA-directed RNA polymerase, mitochondrial [pompepnew.fasta]
  • |||DNA-directed RNA polymerase (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • dna-directed rna polymerase, mitochondrial precursor [Schizosaccharomyces pombe]gi|2398821|emb|CAB16197.1| SPAC26H5.12 [Schizosaccharomyces pombe]gi|7490490|pir||T38431 DNA-directed RNA polymerase precursor, mitochondrial - fission yeast (Schizosaccharo [nrdb_11152004_Chlamydomonas]
  • |rpo41||DNA-directed RNA polymerase|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O13993) DNA-directed RNA polymerase, mitochondrial precursor (EC 2.7.7.6) [pompep4896_normal_reversed]
  • |rpo41||mitochondrial RNA polymerase|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • DNA-directed RNA polymerase, mitochondrial precursor [nr-271106-contam.fasta]
  • SPAC26H5.12 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC26H5.12 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 1120 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISSLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: transcription from mitochondrial promoter [ISSLink to PubMed article]
    mitochondrial genome maintenance [ISSLink to PubMed article]
    Molecular Function: DNA binding [IEA]
    DNA-directed RNA polymerase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIEAYEPYK NELKSKIGKD FIIDLSYKSG TASLFEACVY NGDFLRSKQL LKSFIDHNKG  60
   61 DKILLPMINL YIREIIQRGS FELTDVLSNA KELLQQARLN GDSLTYALLC QASLNPTQRQ 120
  121 LGLPVLHELI HNWRSANGKV IDILMHESVF SPEEVKLIMD QLNIPINNFT PSQLQLLGIT 180
  181 NSTIVGESEN GKDQNGDSSL KEKQPDVETT VTKSANLNAL RSSLSSLLTE SIDLPIDEVS 240
  241 LEFGNQGDTF NLARQKLLEK SAILSAAEVW KSEHESVLNR GNLQVPKNVS SLFYSWYVQL 300
  301 EQLFKEEISL IDDLALNESL DKKNDRLIYG PFLKLLSSKK LAALTIMEVA QLSTNPRYDR 360
  361 GARVTTLLGG LGRSFEREFL SEQIQRQEKN KSYKDKKRLK ELFNDPRKFR QAVKNLRLSN 420
  421 TRDNIVLNPS VDSWPSAIVM KVGSVALCLL LSVAKIEVTA KDLSTGGILK QEVAAFVHTY 480
  481 QYSNGRKVGM IVPHVEFYKL LSRDIEKPHL HPQLLPMLVT PKPWTSWIDG GYYYSRQPLV 540
  541 RLKGALEQVD YLMKASENGQ LDELFKAVSS LGKVSWRINQ RLFNVLIRIW NSGEKFLSIP 600
  601 PREVKCDMPP YPKNSINPRD KVIWHTRRKE LAALKTGAHS QRCDFNYKLE IARAFLNEKF 660
  661 YFPHSLDFRG RAYPLSSHLH HVSNDVCRGL LEFSTGKPLG PKGLNWLKVH LANLFGISKK 720
  721 DFATRQAFVD DNMQEVFDSA DRPLDGNKWW SKADDPFQAL AACFEIAEAV RSGDHESYIS 780
  781 HIPIQQDGTC NGLQHYAALG GDIEGAKQVN LWPSDHPSDV YEAVAEIVRG FLKKDAEAGD 840
  841 EMANFLKDKV TRSVVKPTVM TNVYGVTYVG ARKQISEKLE NIDGMEKLKV ADYANYLTKK 900
  901 VFEALRSLFT QAHEIQDWLS ACCNLITHSL PADYIKEGIK DELTPVVWTT LLNLPIVQPY 960
  961 RNYKSRQIRT NLQTVFIEER DRTATVQPHK QATAFPPNFI HSLDATHMFM TCLKCSEQNI1020
 1021 NFAAVHDSYW THACDVDQMN SLLREAFVLL HSNNIMERLK QEFEERYKGF LVSKKAIKAN1080
 1081 DEDLKAKFGN KSYIPLEFPP LPARGALDLK KVLESKYFFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] PSI-BLAST 3.39794 Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
    2 View Details [204..1120] PSI-BLAST 1000.0 No description for 2pi4A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleotidyltransferase activity
    		•  2.80387066605111 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  2.6108181024665 bayes_pls_golite062009
  • DNA polymerase activity
    		•  2.44559689391189 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  2.0559247272131 bayes_pls_golite062009
  • RNA polymerase activity
    		•  2.0559247272131 bayes_pls_golite062009
  • binding
    		•  1.92492422240469 bayes_pls_golite062009
  • DNA binding
    		•  1.87721092677049 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.77244128755319 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.64235873416087 bayes_pls_golite062009
  • transferase activity
    		•  1.48796361930482 bayes_pls_golite062009
  • chromatin binding
    		•  1.32386525961438 bayes_pls_golite062009
  • catalytic activity
    		•  1.04899053677564 bayes_pls_golite062009
  • protein binding
    		•  0.561579019896047 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.0700154911930899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle