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Protein Overview: rna1

General Information:
Name(s) found: rna1 / SPAC22E12.07 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • Ran GAP Rna1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 386 amino acids

    Gene Ontology:
    Cellular Component: nuclear membrane [IDALink to PubMed articleLink to PubMed article]
    perinuclear region of cytoplasm [IEA]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: Ran protein signal transduction [TASLink to PubMed article]
    nucleocytoplasmic transport [IGILink to PubMed article]
    chromatin silencing at centromere [IMPLink to PubMed article]
    kinetochore organization [IGILink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    [NOT]chromatin silencing at telomere [IMPLink to PubMed article]
    Molecular Function: GTPase activator activity [TASLink to PubMed article]
    Ran GTPase activator activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRFSIEGKS LKLDAITTED EKSVFAVLLE DDSVKEIVLS GNTIGTEAAR WLSENIASKK  60
   61 DLEIAEFSDI FTGRVKDEIP EALRLLLQAL LKCPKLHTVR LSDNAFGPTA QEPLIDFLSK 120
  121 HTPLEHLYLH NNGLGPQAGA KIARALQELA VNKKAKNAPP LRSIICGRNR LENGSMKEWA 180
  181 KTFQSHRLLH TVKMVQNGIR PEGIEHLLLE GLAYCQELKV LDLQDNTFTH LGSSALAIAL 240
  241 KSWPNLRELG LNDCLLSARG AAAVVDAFSK LENIGLQTLR LQYNEIELDA VRTLKTVIDE 300
  301 KMPDLLFLEL NGNRFSEEDD VVDEIREVFS TRGRGELDEL DDMEELTDEE EEDEEEEAES 360
  361 QSPEPETSEE EKEDKELADE LSKAHI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..386] PSI-BLAST 23.69897 Rna1p (RanGAP1), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.665591019824 bayes_pls_golite062009
  • Ran GTPase activator activity
    		•  2.34047639993996 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.29984527283876 bayes_pls_golite062009
  • protein binding
    		•  1.61093336454573 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.2949624636683 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.28868732384901 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.2181060000102 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.20424046001063 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  1.08702516953191 bayes_pls_golite062009
  • actin binding
    		•  0.79104197850666 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.709760900885283 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.283509641791735 bayes_pls_golite062009
  • catalytic activity
    		•  0.143741655309638 bayes_pls_golite062009
  • tropomyosin binding
    		•  0.102409833136912 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle