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Protein Overview: pim1

General Information:
Name(s) found: pim1 / SPBC557.03c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • GDP/GTP exchange factor (RanGEF) [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 539 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    nuclear chromatin [NAS]
    Biological Process: Ran protein signal transduction [IGILink to PubMed article]
    mRNA export from nucleus [IMPLink to PubMed article]
    spindle assembly [TASLink to PubMed article]
    rRNA export from nucleus [ISS]
    mitotic cell cycle checkpoint [IMPLink to PubMed article]
    small GTPase mediated signal transduction [ICLink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    mitotic metaphase/anaphase transition [IMPLink to PubMed article]
    regulation of mitotic cell cycle [IMPLink to PubMed article]
    regulation of chromosome condensation [IGILink to PubMed article]
    Molecular Function: Ran guanyl-nucleotide exchange factor activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSNRSTRSS TKREEVSKNG VEKRELDESD VMKNGKKPVK RAKVSSLPKP VRVPGSAKRI  60
   61 NKIPELPTER LNVYVFGSGS MNELGMGEEE MDVVYRPRLN PILSTDKVGV VDLAVGGMHS 120
  121 AALSHDGRVY TWGVNDDYAL GRLTKDQKDE NGDKVDNDLL EGTPSKVEGA LSHLRVTKVI 180
  181 CSDNLTAAIT DNGCCFTWGT FRCSDGVLGY SDSQKRTAEP TQMRLPEICQ LATGTDHIIA 240
  241 LTTTGKVYTW GNGQQFQLGR RMLERRRLQG LTPQPLALKN IISVGAGSYH SFAIDNKGRV 300
  301 YAWGLNITRQ CGIEVEDEEE GAVITKPTLV DALEGYNVKS ITGGEHHTLA LLEDGRVLAW 360
  361 GRDDRHQLGI PDNALPETVV KDEKGNNYYL STPTIIPGLT NVIQVVCGTH HNLAVTSDGK 420
  421 VYSWGSAENY EVGQGDNDED VAVPTLVRSK AIKEVAIRVA GAGGQFSIIA GIPNASEEPV 480
  481 ANGIKSEPEN EKKLKTEETS KTDDSPVTDA KPDVTSNGEP STATSESKDS VLEPSSTTA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..539] PSI-BLAST 76.0 Regulator of chromosome condensation RCC1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTPase regulator activity
    		•  2.91135341067617 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.89051221007497 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  2.78763396258796 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  2.67769296699335 bayes_pls_golite062009
  • Ras guanyl-nucleotide exchange factor activity
    		•  2.54000969805561 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.16356879283979 bayes_pls_golite062009
  • Ran guanyl-nucleotide exchange factor activity
    		•  1.99390987036621 bayes_pls_golite062009
  • binding
    		•  1.94765972306941 bayes_pls_golite062009
  • chromatin binding
    		•  1.1028187707197 bayes_pls_golite062009
  • histone binding
    		•  0.76536700536926 bayes_pls_golite062009
  • protein binding
    		•  0.568399753749593 bayes_pls_golite062009
  • catalytic activity
    		•  0.261970921089142 bayes_pls_golite062009
  • ligase activity
    		•  0.233377687886995 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle