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Protein Overview: ura4

General Information:
Name(s) found: ura4 / SPCC330.05c [Sanger Pombe]
Description(s) found:
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  • gi|5134|emb|CAA32157.1| orotidine-5'-phosphate (OMP) decarboxylase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|3646446|emb|CAA20910.1| orotidine 5'-phosphate decarboxylase Ura4 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075205|ref|NP_587705.1| orotidine 5'-phosphate decarboxylase Ura4 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|118369|sp|P14965.1|PYRF_SCHPO RecName: Full=Orotidine 5'-phosphate decarboxylase; AltName: Full=OMP decarboxylase; Short=OMPdecase; Short=OMPDCase; AltName: Full=Uridine 5'-monophosphate synthase; Short=UMP synthase [NCBI NR]
  • pir||S08503 orotidine 5'-phosphate decarboxylase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • orotidine 5'-phosphate decarboxylase Ura4 [Sanger Pombe]
  • Orotidine 5'-phosphate decarboxylase OS=Schizosaccharomyces pombe GN=ura4 PE=2 SV=1 [Swiss-Prot]
  • OROTIDINE 5'-PHOSPHATE DECARBOXYLASE; SIMILAR TO S. CEREVISIAE URA3: P14965; [pompepVF.fasta]
  • OROTIDINE 5'-PHOSPHATE DECARBOXYLASE: P14965; [pompepV13]
  • Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP decarboxylase) (OMPDCase) (OMPdecase) (Uridine 5'-monophosphate synthase) (UMP synthase) [pompep4896]
  • |ura4||orotidine 5'-phosphate decarboxylase (PMID 2834100) [pompepnew.fasta]
  • |ura4||orotidine 5'-phosphate decarboxylase activity (PMID 2834100)|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • |ura4||orotidine 5'-phosphate decarboxylase activity |Schizosaccharomyces pombe|chr 3|||Manual [pompep2242005.fasta]
  • ura4+ protein [Degron tagging vector pSMUG2+]gi|37654596|gb|AAQ96630.1| ura4+ protein [YFP Integration vector pSMUY2+]gi|37654592|gb|AAQ96627.1| ura4+ protein [CFP Integration vector pSMUC2+]gi|19075205|ref|NP_587705.1| orotidine 5'-phosphate decarboxy [nrdb_11152004_Chlamydomonas]
  • (P14965) Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP decarboxylase) (OMPDCase) (OMPdecase) (Uridine 5'-monophosphate synthase) (UMP synthase) [pompep4896_normal_reversed]
  • |ura4||orotidine 5'-phosphate decarboxylase Ura4|Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Orotidine 5'-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase) (Uridine 5'-monophosphate synthase) (UMP synthase) [nr-271106-contam.fasta]
  • hypothetical protein SPCC330.05c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPCC330.05c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • orotidine-5'-phosphate (OMP) decarboxylase [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Orotidine 5'-phosphate decarboxylase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ura4 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 264 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: 'de novo' pyrimidine base biosynthetic process [IGILink to PubMed article]
    Molecular Function: orotidine-5'-phosphate decarboxylase activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDARVFQSYS ARAEGMKNPI AKELLALMEE KQSNLSVAVD LTKKSEILEL VDKIGPYVCV  60
   61 IKTHIDVVED FDQDMVEKLV ALGKKHRFLI FEDRKFADIG NTVKLQYASG VYKIASWAHI 120
  121 TNCHTVPGEG IIQGLKEVGL PLGRGLLLLA EMSSKGSLAT GSYTEKTLEW FEKHTDFCFG 180
  181 FIAGRRFPNL QSDYITMSPG IGLDVKGDGL GQQYRTPEEV IVNCGSDIII VGRGVYGAGR 240
  241 NPVVEAKRYR EAGWKAYQQR LSQH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264] PSI-BLAST 74.69897 Orotidine 5'-monophosphate decarboxylase (OMP decarboxylase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • orotidine-5'-phosphate decarboxylase activity
    		•  2.87717797280068 bayes_pls_golite062009
  • catalytic activity
    		•  2.44231061702877 bayes_pls_golite062009
  • binding
    		•  1.26628194990205 bayes_pls_golite062009
  • ribulose-phosphate 3-epimerase activity
    		•  0.982517927791965 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  0.83446736141993 bayes_pls_golite062009
  • indole-3-glycerol-phosphate synthase activity
    		•  0.700596444201789 bayes_pls_golite062009
  • phosphoribosylanthranilate isomerase activity
    		•  0.644387926981014 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  0.580372404365274 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.54291459543716 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  0.108467338662618 bayes_pls_golite062009
  • protein binding
    		•  0.014429239696785 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle